KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLYCD
All Species:
38.48
Human Site:
Y405
Identified Species:
65.13
UniProt:
O95822
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95822
NP_036345.2
493
55003
Y405
L
M
R
L
C
A
W
Y
L
Y
G
E
K
H
R
Chimpanzee
Pan troglodytes
XP_523518
493
54957
Y405
L
M
R
L
C
A
W
Y
L
Y
G
E
K
H
R
Rhesus Macaque
Macaca mulatta
XP_001112117
493
54893
Y405
L
M
R
L
C
A
W
Y
L
Y
G
E
K
H
R
Dog
Lupus familis
XP_852152
442
48705
Y354
L
M
R
L
C
A
W
Y
L
F
G
E
K
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99J39
492
54718
Y404
L
M
R
L
C
A
W
Y
L
Y
G
E
K
H
R
Rat
Rattus norvegicus
Q920F5
492
54744
Y404
L
M
R
L
C
A
W
Y
L
Y
G
E
K
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508710
449
50992
Y361
L
M
R
L
C
A
W
Y
L
F
G
E
K
H
R
Chicken
Gallus gallus
XP_414174
547
60873
Y459
L
M
R
L
C
A
W
Y
L
Y
G
E
K
H
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082972
504
57530
Y416
L
M
R
L
C
A
W
Y
L
F
G
E
K
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625201
377
44289
Y301
Y
K
E
K
R
R
N
Y
A
L
D
S
V
A
N
Nematode Worm
Caenorhab. elegans
NP_001022561
442
50154
Y363
L
M
Y
A
C
A
H
Y
L
C
N
A
K
R
N
Sea Urchin
Strong. purpuratus
XP_001184115
408
46014
E332
K
K
V
I
V
T
N
E
W
V
K
S
E
S
L
Poplar Tree
Populus trichocarpa
XP_002331555
468
52961
E355
L
L
T
S
K
N
Y
E
W
T
S
S
A
E
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192341
518
58433
W418
L
S
V
K
N
C
D
W
A
T
S
P
R
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.5
74.8
N.A.
88
88.2
N.A.
67.7
65
N.A.
58.3
N.A.
N.A.
39.7
34.8
41.7
Protein Similarity:
100
98.9
97.3
80.7
N.A.
91.8
92.4
N.A.
76.2
75.5
N.A.
71.6
N.A.
N.A.
53.9
51.3
54.9
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
100
N.A.
86.6
N.A.
N.A.
6.6
46.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
6.6
46.6
13.3
Percent
Protein Identity:
38.1
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
54.1
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
72
0
0
15
0
0
8
8
8
0
% A
% Cys:
0
0
0
0
72
8
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
15
0
0
0
65
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
22
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
58
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
15
0
15
8
0
0
0
0
0
8
0
72
0
0
% K
% Leu:
86
8
0
65
0
0
0
0
72
8
0
0
0
8
22
% L
% Met:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
15
0
0
0
8
0
0
0
15
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
65
0
8
8
0
0
0
0
0
0
8
15
65
% R
% Ser:
0
8
0
8
0
0
0
0
0
0
15
22
0
8
0
% S
% Thr:
0
0
8
0
0
8
0
0
0
15
0
0
0
0
0
% T
% Val:
0
0
15
0
8
0
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
65
8
15
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
8
79
0
43
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _