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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLYCD
All Species:
36.67
Human Site:
Y454
Identified Species:
62.05
UniProt:
O95822
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95822
NP_036345.2
493
55003
Y454
S
C
G
L
M
A
N
Y
R
Y
F
L
E
E
T
Chimpanzee
Pan troglodytes
XP_523518
493
54957
Y454
S
C
G
L
M
A
N
Y
R
Y
F
L
E
E
T
Rhesus Macaque
Macaca mulatta
XP_001112117
493
54893
Y454
S
C
G
L
M
A
N
Y
R
Y
F
L
E
E
T
Dog
Lupus familis
XP_852152
442
48705
Y403
S
C
G
L
M
V
N
Y
R
Y
Y
P
A
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99J39
492
54718
Y453
S
C
G
L
M
V
N
Y
R
Y
Y
L
E
E
T
Rat
Rattus norvegicus
Q920F5
492
54744
Y453
S
C
G
L
M
V
N
Y
R
Y
Y
L
E
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508710
449
50992
Y410
S
C
G
L
M
V
N
Y
R
Y
F
L
E
E
T
Chicken
Gallus gallus
XP_414174
547
60873
Y508
A
C
G
M
M
V
N
Y
R
Y
F
L
E
D
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082972
504
57530
Y465
S
C
G
I
M
V
N
Y
R
Y
F
L
Q
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625201
377
44289
V339
G
N
S
C
G
I
M
V
N
Y
R
Y
Y
L
H
Nematode Worm
Caenorhab. elegans
NP_001022561
442
50154
N404
T
S
H
R
G
I
N
N
S
F
G
I
M
V
N
Sea Urchin
Strong. purpuratus
XP_001184115
408
46014
I370
M
A
L
N
P
V
V
I
D
D
D
E
E
L
F
Poplar Tree
Populus trichocarpa
XP_002331555
468
52961
Y426
S
G
G
I
M
V
N
Y
V
Y
R
V
E
C
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192341
518
58433
L458
D
S
V
A
N
F
H
L
Q
N
G
A
M
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.5
74.8
N.A.
88
88.2
N.A.
67.7
65
N.A.
58.3
N.A.
N.A.
39.7
34.8
41.7
Protein Similarity:
100
98.9
97.3
80.7
N.A.
91.8
92.4
N.A.
76.2
75.5
N.A.
71.6
N.A.
N.A.
53.9
51.3
54.9
P-Site Identity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
93.3
73.3
N.A.
80
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
100
100
100
80
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
6.6
26.6
6.6
Percent
Protein Identity:
38.1
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
54.1
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
22
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
65
0
8
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
8
8
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
65
58
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
43
0
0
0
8
% F
% Gly:
8
8
72
0
15
0
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
15
0
15
0
8
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
50
0
0
0
8
0
0
0
58
0
15
0
% L
% Met:
8
0
0
8
72
0
8
0
0
0
0
0
15
0
0
% M
% Asn:
0
8
0
8
8
0
79
8
8
8
0
0
0
0
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
65
0
15
0
0
0
0
% R
% Ser:
65
15
8
0
0
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
65
% T
% Val:
0
0
8
0
0
58
8
8
8
0
0
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
72
0
79
22
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _