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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLYCD
All Species:
26.06
Human Site:
Y54
Identified Species:
44.1
UniProt:
O95822
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95822
NP_036345.2
493
55003
Y54
A
V
P
P
T
P
A
Y
E
L
R
E
K
T
P
Chimpanzee
Pan troglodytes
XP_523518
493
54957
Y54
A
V
P
P
T
P
A
Y
E
L
R
E
K
T
P
Rhesus Macaque
Macaca mulatta
XP_001112117
493
54893
Y54
A
V
P
P
T
P
A
Y
E
L
R
E
K
T
P
Dog
Lupus familis
XP_852152
442
48705
E44
G
G
L
A
E
A
A
E
R
A
D
L
L
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99J39
492
54718
Y53
A
V
P
P
T
P
A
Y
E
L
R
E
K
T
P
Rat
Rattus norvegicus
Q920F5
492
54744
Y53
A
V
P
P
T
P
A
Y
E
L
R
E
K
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508710
449
50992
F44
A
E
H
C
P
E
R
F
G
M
E
K
R
R
V
Chicken
Gallus gallus
XP_414174
547
60873
Y108
S
V
P
P
L
P
P
Y
E
T
K
E
K
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082972
504
57530
Y63
T
V
A
P
L
P
S
Y
E
M
R
D
K
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625201
377
44289
R9
I
S
Y
E
R
N
L
R
N
V
L
T
P
D
Y
Nematode Worm
Caenorhab. elegans
NP_001022561
442
50154
E50
L
Y
A
N
S
T
P
E
T
R
K
S
I
F
V
Sea Urchin
Strong. purpuratus
XP_001184115
408
46014
H39
A
S
G
M
G
V
R
H
D
K
I
L
T
E
A
Poplar Tree
Populus trichocarpa
XP_002331555
468
52961
I48
K
E
Y
D
L
N
R
I
Q
V
R
E
L
L
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192341
518
58433
S67
V
V
R
E
T
M
H
S
A
I
S
A
S
K
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.5
74.8
N.A.
88
88.2
N.A.
67.7
65
N.A.
58.3
N.A.
N.A.
39.7
34.8
41.7
Protein Similarity:
100
98.9
97.3
80.7
N.A.
91.8
92.4
N.A.
76.2
75.5
N.A.
71.6
N.A.
N.A.
53.9
51.3
54.9
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
6.6
60
N.A.
53.3
N.A.
N.A.
0
0
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
33.3
73.3
N.A.
80
N.A.
N.A.
6.6
13.3
20
Percent
Protein Identity:
38.1
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
54.1
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
15
8
0
8
43
0
8
8
0
8
0
8
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
0
8
8
0
8
0
% D
% Glu:
0
15
0
15
8
8
0
15
50
0
8
50
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
8
8
8
0
8
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
8
8
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
8
15
8
50
8
8
% K
% Leu:
8
0
8
0
22
0
8
0
0
36
8
15
15
8
0
% L
% Met:
0
0
0
8
0
8
0
0
0
15
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
15
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
43
50
8
50
15
0
0
0
0
0
8
0
50
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
0
22
8
8
8
50
0
8
8
8
% R
% Ser:
8
15
0
0
8
0
8
8
0
0
8
8
8
15
0
% S
% Thr:
8
0
0
0
43
8
0
0
8
8
0
8
8
36
8
% T
% Val:
8
58
0
0
0
8
0
0
0
15
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
15
0
0
0
0
50
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _