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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYZL1
All Species:
30.91
Human Site:
T250
Identified Species:
75.56
UniProt:
O95825
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95825
NP_665857.2
349
38697
T250
P
H
K
H
D
I
I
T
L
L
G
V
G
G
H
Chimpanzee
Pan troglodytes
XP_531441
456
50238
T357
P
H
K
H
D
I
I
T
L
L
G
V
G
G
H
Rhesus Macaque
Macaca mulatta
XP_001090445
350
38813
T251
P
H
K
H
D
I
I
T
L
L
G
V
G
G
H
Dog
Lupus familis
XP_535585
349
38682
T250
P
H
K
H
D
I
I
T
L
L
G
V
G
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q921W4
348
38707
T249
P
H
K
H
D
I
I
T
L
L
G
V
G
G
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513816
349
38685
L250
P
H
K
H
D
I
I
L
L
L
S
V
G
G
H
Chicken
Gallus gallus
XP_416714
487
53949
T388
P
H
K
H
D
I
I
T
L
L
G
V
G
G
N
Frog
Xenopus laevis
NP_001085430
348
38579
T249
P
H
K
H
D
I
I
T
L
L
S
V
G
S
H
Zebra Danio
Brachydanio rerio
NP_001002633
345
38479
T246
P
H
K
H
D
L
L
T
L
L
S
V
G
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782474
166
18320
N77
G
V
D
C
I
L
D
N
G
V
N
M
Y
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.3
98.5
93.6
N.A.
90.5
N.A.
N.A.
78.5
56.6
67.3
59.8
N.A.
N.A.
N.A.
N.A.
21.7
Protein Similarity:
100
76.5
99.7
96.5
N.A.
95.1
N.A.
N.A.
90.5
65.3
82.5
77
N.A.
N.A.
N.A.
N.A.
32.6
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
93.3
86.6
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
100
86.6
93.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
90
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
10
0
60
0
90
80
0
% G
% His:
0
90
0
90
0
0
0
0
0
0
0
0
0
0
80
% H
% Ile:
0
0
0
0
10
80
80
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
90
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
20
10
10
90
90
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
20
% N
% Pro:
90
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
30
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
10
0
90
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _