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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRYZL1 All Species: 30.91
Human Site: T250 Identified Species: 75.56
UniProt: O95825 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95825 NP_665857.2 349 38697 T250 P H K H D I I T L L G V G G H
Chimpanzee Pan troglodytes XP_531441 456 50238 T357 P H K H D I I T L L G V G G H
Rhesus Macaque Macaca mulatta XP_001090445 350 38813 T251 P H K H D I I T L L G V G G H
Dog Lupus familis XP_535585 349 38682 T250 P H K H D I I T L L G V G G H
Cat Felis silvestris
Mouse Mus musculus Q921W4 348 38707 T249 P H K H D I I T L L G V G G H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513816 349 38685 L250 P H K H D I I L L L S V G G H
Chicken Gallus gallus XP_416714 487 53949 T388 P H K H D I I T L L G V G G N
Frog Xenopus laevis NP_001085430 348 38579 T249 P H K H D I I T L L S V G S H
Zebra Danio Brachydanio rerio NP_001002633 345 38479 T246 P H K H D L L T L L S V G G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782474 166 18320 N77 G V D C I L D N G V N M Y P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.3 98.5 93.6 N.A. 90.5 N.A. N.A. 78.5 56.6 67.3 59.8 N.A. N.A. N.A. N.A. 21.7
Protein Similarity: 100 76.5 99.7 96.5 N.A. 95.1 N.A. N.A. 90.5 65.3 82.5 77 N.A. N.A. N.A. N.A. 32.6
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 86.6 93.3 86.6 80 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 86.6 100 86.6 93.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 90 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 10 0 60 0 90 80 0 % G
% His: 0 90 0 90 0 0 0 0 0 0 0 0 0 0 80 % H
% Ile: 0 0 0 0 10 80 80 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 90 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 20 10 10 90 90 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 20 % N
% Pro: 90 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 30 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 10 0 90 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _