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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIFM1
All Species:
19.39
Human Site:
S536
Identified Species:
42.67
UniProt:
O95831
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95831
NP_004199.1
613
66901
S536
R
S
E
S
E
T
E
S
E
A
S
E
I
T
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092146
613
66900
S536
R
S
E
S
E
T
E
S
E
A
S
E
I
A
I
Dog
Lupus familis
XP_538170
613
66817
S536
R
S
E
S
E
T
E
S
E
A
S
E
I
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0X1
612
66747
S535
R
S
E
S
E
T
E
S
E
A
S
E
I
T
I
Rat
Rattus norvegicus
Q9JM53
612
66704
S535
R
S
E
S
E
T
E
S
E
A
S
E
I
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007491
591
64503
A514
R
S
E
S
E
T
E
A
E
A
S
E
V
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662031
750
81177
A675
R
S
E
S
E
T
E
A
V
A
G
V
L
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQ79
739
81198
S662
V
P
E
T
S
T
S
S
S
Q
S
S
K
S
D
Honey Bee
Apis mellifera
XP_395674
661
74313
E578
K
K
K
L
N
S
T
E
T
Q
N
P
I
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202402
409
44470
L371
K
V
V
V
G
M
L
L
W
N
I
F
N
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SR59
441
48344
Q403
V
F
L
E
G
G
T
Q
E
E
H
K
A
I
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
94.2
N.A.
92.1
92.5
N.A.
N.A.
76.1
N.A.
59.3
N.A.
40
44
N.A.
43.7
Protein Similarity:
100
N.A.
99.1
96.7
N.A.
96.7
96.4
N.A.
N.A.
85.3
N.A.
68.1
N.A.
54.9
60.8
N.A.
55.7
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
100
100
N.A.
N.A.
80
N.A.
53.3
N.A.
26.6
6.6
N.A.
0
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
100
100
N.A.
N.A.
93.3
N.A.
73.3
N.A.
40
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
19
0
64
0
0
10
19
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
73
10
64
0
64
10
64
10
0
55
0
19
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
19
10
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
55
10
46
% I
% Lys:
19
10
10
0
0
0
0
0
0
0
0
10
10
10
0
% K
% Leu:
0
0
10
10
0
0
10
10
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
0
0
10
10
0
10
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
19
0
0
0
0
0
% Q
% Arg:
64
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
64
0
64
10
10
10
55
10
0
64
10
0
10
10
% S
% Thr:
0
0
0
10
0
73
19
0
10
0
0
0
0
28
0
% T
% Val:
19
10
10
10
0
0
0
0
10
0
0
10
10
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _