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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIFM1
All Species:
9.7
Human Site:
T547
Identified Species:
21.33
UniProt:
O95831
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95831
NP_004199.1
613
66901
T547
E
I
T
I
P
P
S
T
P
A
V
P
Q
A
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092146
613
66900
T547
E
I
A
I
P
P
S
T
P
A
V
P
Q
A
P
Dog
Lupus familis
XP_538170
613
66817
N547
E
I
A
V
P
P
S
N
P
A
V
P
Q
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0X1
612
66747
A546
E
I
T
I
P
P
S
A
P
A
V
P
Q
V
P
Rat
Rattus norvegicus
Q9JM53
612
66704
D546
E
I
T
I
P
P
S
D
P
A
V
P
Q
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007491
591
64503
S525
E
V
P
I
S
P
S
S
S
P
T
P
Q
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662031
750
81177
T686
V
L
E
V
G
T
V
T
P
A
P
P
V
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQ79
739
81198
S673
S
K
S
D
A
G
A
S
Q
D
G
V
T
C
D
Honey Bee
Apis mellifera
XP_395674
661
74313
E589
P
I
E
S
N
L
K
E
N
D
K
S
I
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202402
409
44470
R382
F
N
K
M
P
I
A
R
K
V
L
K
D
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SR59
441
48344
R414
K
A
I
A
K
V
A
R
A
Q
P
S
V
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
94.2
N.A.
92.1
92.5
N.A.
N.A.
76.1
N.A.
59.3
N.A.
40
44
N.A.
43.7
Protein Similarity:
100
N.A.
99.1
96.7
N.A.
96.7
96.4
N.A.
N.A.
85.3
N.A.
68.1
N.A.
54.9
60.8
N.A.
55.7
P-Site Identity:
100
N.A.
93.3
73.3
N.A.
86.6
86.6
N.A.
N.A.
46.6
N.A.
26.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
93.3
80
N.A.
86.6
86.6
N.A.
N.A.
60
N.A.
40
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
10
10
0
28
10
10
55
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
19
0
0
10
0
10
% D
% Glu:
55
0
19
0
0
0
0
10
0
0
0
0
0
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
55
10
46
0
10
0
0
0
0
0
0
10
0
10
% I
% Lys:
10
10
10
0
10
0
10
0
10
0
10
10
0
0
0
% K
% Leu:
0
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
10
0
10
0
55
55
0
0
55
10
19
64
0
0
55
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
0
0
55
10
19
% Q
% Arg:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
10
10
0
55
19
10
0
0
19
0
10
10
% S
% Thr:
0
0
28
0
0
10
0
28
0
0
10
0
10
10
0
% T
% Val:
10
10
0
19
0
10
10
0
0
10
46
10
19
28
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _