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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIFM1
All Species:
19.09
Human Site:
Y85
Identified Species:
42
UniProt:
O95831
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95831
NP_004199.1
613
66901
Y85
V
G
A
G
A
Y
A
Y
K
T
M
K
E
D
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092146
613
66900
Y85
V
G
A
G
V
Y
A
Y
K
I
I
K
E
D
E
Dog
Lupus familis
XP_538170
613
66817
Y85
I
G
A
G
A
Y
A
Y
K
T
I
K
D
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0X1
612
66747
Y84
I
G
A
G
A
Y
A
Y
K
T
I
K
E
D
Q
Rat
Rattus norvegicus
Q9JM53
612
66704
Y84
I
G
A
G
A
Y
A
Y
K
T
I
K
E
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007491
591
64503
G63
I
V
G
G
T
V
T
G
A
G
A
Y
V
Y
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662031
750
81177
V224
P
V
V
E
S
E
P
V
P
V
V
S
T
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQ79
739
81198
G208
L
A
A
L
L
A
G
G
F
L
A
W
F
M
T
Honey Bee
Apis mellifera
XP_395674
661
74313
Y126
I
I
A
G
V
A
I
Y
A
I
S
S
T
N
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202402
409
44470
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SR59
441
48344
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
94.2
N.A.
92.1
92.5
N.A.
N.A.
76.1
N.A.
59.3
N.A.
40
44
N.A.
43.7
Protein Similarity:
100
N.A.
99.1
96.7
N.A.
96.7
96.4
N.A.
N.A.
85.3
N.A.
68.1
N.A.
54.9
60.8
N.A.
55.7
P-Site Identity:
100
N.A.
80
73.3
N.A.
80
80
N.A.
N.A.
6.6
N.A.
0
N.A.
6.6
20
N.A.
0
P-Site Similarity:
100
N.A.
86.6
100
N.A.
100
100
N.A.
N.A.
20
N.A.
20
N.A.
13.3
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
64
0
37
19
46
0
19
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
46
0
% D
% Glu:
0
0
0
10
0
10
0
0
0
0
0
0
37
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% F
% Gly:
0
46
10
64
0
0
10
19
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
46
10
0
0
0
0
10
0
0
19
37
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
46
0
0
46
0
0
10
% K
% Leu:
10
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
28
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
0
0
10
19
0
0
0
% S
% Thr:
0
0
0
0
10
0
10
0
0
37
0
0
19
0
10
% T
% Val:
19
19
10
0
19
10
0
10
0
10
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% W
% Tyr:
0
0
0
0
0
46
0
55
0
0
0
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _