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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN1
All Species:
28.67
Human Site:
S206
Identified Species:
70.09
UniProt:
O95832
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95832
NP_066924.1
211
22744
S206
Y
P
K
P
A
P
S
S
G
K
D
Y
V
_
_
Chimpanzee
Pan troglodytes
XP_511974
211
22381
S206
R
S
Y
P
K
S
N
S
S
K
E
Y
V
_
_
Rhesus Macaque
Macaca mulatta
XP_001093143
211
22753
S206
Y
P
K
P
A
P
S
S
G
K
D
Y
V
_
_
Dog
Lupus familis
XP_850248
211
22768
S206
Y
P
K
P
A
P
S
S
G
K
D
Y
V
_
_
Cat
Felis silvestris
Mouse
Mus musculus
O88551
211
22862
S206
Y
P
K
P
T
P
S
S
G
K
D
Y
V
_
_
Rat
Rattus norvegicus
P56745
211
22824
S206
Y
P
K
P
T
P
S
S
G
K
D
Y
V
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511907
211
22724
S206
Y
P
K
P
A
P
S
S
G
K
D
Y
V
_
_
Chicken
Gallus gallus
NP_001013629
211
22608
T206
Y
P
K
N
A
P
S
T
G
K
D
Y
V
_
_
Frog
Xenopus laevis
NP_001079445
211
22458
A206
Y
N
K
S
A
P
P
A
G
K
D
Y
V
_
_
Zebra Danio
Brachydanio rerio
Q9YH92
215
22846
R206
S
R
P
V
K
S
S
R
P
P
S
S
S
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.6
99.5
93.3
N.A.
90.5
91.4
N.A.
87.1
74.4
67.3
53.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.5
99.5
99.5
N.A.
96.6
97.1
N.A.
95.7
85.7
82.9
72
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
38.4
100
100
N.A.
92.3
92.3
N.A.
100
84.6
69.2
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.8
100
100
N.A.
92.3
92.3
N.A.
100
92.3
76.9
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
60
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
80
0
20
0
0
0
0
90
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
70
10
70
0
80
10
0
10
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
10
0
20
80
70
10
0
10
10
10
0
0
% S
% Thr:
0
0
0
0
20
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
90
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
80
0
10
0
0
0
0
0
0
0
0
90
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
90
90
% _