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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLIC3
All Species:
15.76
Human Site:
S49
Identified Species:
38.52
UniProt:
O95833
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95833
NP_004660.2
236
26648
S49
T
T
V
D
T
R
R
S
P
D
V
L
K
D
F
Chimpanzee
Pan troglodytes
XP_520422
236
26612
S49
T
T
V
D
T
R
R
S
P
D
V
L
K
D
F
Rhesus Macaque
Macaca mulatta
XP_001117823
236
26290
S49
Y
H
G
G
H
A
Q
S
P
D
V
L
K
D
F
Dog
Lupus familis
XP_848692
254
28726
S50
T
T
V
D
T
R
R
S
L
D
V
L
K
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7P7
237
26827
A50
T
T
V
D
T
R
R
A
L
D
V
L
K
D
F
Rat
Rattus norvegicus
Q9EPT8
251
28280
K59
T
T
V
D
L
K
R
K
P
A
D
L
H
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514389
305
33825
S67
T
T
V
D
T
K
R
S
L
D
V
L
K
D
F
Chicken
Gallus gallus
NP_001026285
244
28116
K54
T
T
V
D
M
T
R
K
P
E
E
L
K
D
L
Frog
Xenopus laevis
NP_001086217
240
27954
A52
T
T
V
D
M
K
R
A
P
E
V
L
K
D
L
Zebra Danio
Brachydanio rerio
NP_955818
239
27154
A50
T
T
V
D
M
K
R
A
P
E
V
L
K
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
86
82.6
N.A.
90.7
49
N.A.
52.4
48.7
61.2
58.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
87.2
86.6
N.A.
94
62.5
N.A.
62.2
64.7
77.9
74.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
93.3
N.A.
86.6
46.6
N.A.
86.6
60
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
60
93.3
N.A.
93.3
60
N.A.
93.3
66.6
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
30
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
90
0
0
0
0
0
60
10
0
0
90
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
30
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% F
% Gly:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
40
0
20
0
0
0
0
90
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
30
0
0
100
0
0
40
% L
% Met:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
40
90
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
90
90
0
0
50
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
90
0
0
0
0
0
0
0
80
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _