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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML2
All Species:
40.91
Human Site:
S497
Identified Species:
75
UniProt:
O95834
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95834
NP_036287.1
649
70679
S497
D
Q
G
G
R
K
V
S
R
L
G
K
C
S
G
Chimpanzee
Pan troglodytes
XP_001165936
649
70646
S497
D
Q
G
G
R
K
V
S
R
L
G
K
C
S
G
Rhesus Macaque
Macaca mulatta
XP_001110928
815
88569
S663
D
Q
G
G
R
K
V
S
R
L
G
K
C
S
G
Dog
Lupus familis
XP_852371
649
70597
S497
D
Q
G
G
R
K
V
S
R
L
G
K
C
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNG5
649
70715
S497
D
Q
G
G
R
K
V
S
R
L
G
K
C
S
G
Rat
Rattus norvegicus
Q6P6T4
649
70692
S497
D
Q
G
G
R
K
V
S
R
L
G
K
C
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
S708
N
D
N
G
R
K
Y
S
R
I
G
K
C
S
G
Chicken
Gallus gallus
XP_421362
815
90017
T663
N
E
N
G
R
K
Y
T
R
I
G
K
C
S
G
Frog
Xenopus laevis
Q2TAF3
927
102313
S654
S
E
N
G
R
K
Y
S
R
Y
G
K
C
T
G
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
S653
T
E
N
G
K
K
Y
S
R
V
G
K
C
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
N923
G
F
S
Y
K
K
V
N
K
I
R
G
S
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
R738
D
P
H
L
T
I
Y
R
I
D
A
S
K
N
L
Sea Urchin
Strong. purpuratus
Q26613
686
75435
S534
T
E
E
G
R
K
Y
S
K
V
G
K
C
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
78.7
97.3
N.A.
94.9
93.9
N.A.
51.8
54.4
41.7
57.6
N.A.
23.7
N.A.
23.5
53.9
Protein Similarity:
100
100
79.5
99
N.A.
97.6
97.2
N.A.
63.1
66.6
55.2
68.8
N.A.
35.8
N.A.
40.1
71.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
66.6
60
60
53.3
N.A.
13.3
N.A.
6.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
86.6
73.3
80
N.A.
40
N.A.
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
85
0
0
% C
% Asp:
54
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
31
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
47
85
0
0
0
0
0
0
85
8
0
0
85
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
8
24
0
0
0
0
0
% I
% Lys:
0
0
0
0
16
93
0
0
16
0
0
85
8
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
0
47
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
31
0
0
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
47
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
77
0
0
8
77
0
8
0
0
0
0
% R
% Ser:
8
0
8
0
0
0
0
77
0
0
0
8
8
70
0
% S
% Thr:
16
0
0
0
8
0
0
8
0
0
0
0
0
16
0
% T
% Val:
0
0
0
0
0
0
54
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
47
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _