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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EML2 All Species: 30.91
Human Site: T488 Identified Species: 56.67
UniProt: O95834 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95834 NP_036287.1 649 70679 T488 D N L V Y V Y T V D Q G G R K
Chimpanzee Pan troglodytes XP_001165936 649 70646 T488 D N L V Y V Y T V D Q G G R K
Rhesus Macaque Macaca mulatta XP_001110928 815 88569 T654 D N L V Y V Y T V D Q G G R K
Dog Lupus familis XP_852371 649 70597 T488 D N L V Y V Y T V D Q G G R K
Cat Felis silvestris
Mouse Mus musculus Q7TNG5 649 70715 T488 D N L V Y V Y T V D Q G G R K
Rat Rattus norvegicus Q6P6T4 649 70692 T488 D N L V Y V Y T V D Q G G R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512831 860 95042 G699 D N C I Y I Y G V N D N G R K
Chicken Gallus gallus XP_421362 815 90017 G654 D N S I Y I Y G V N E N G R K
Frog Xenopus laevis Q2TAF3 927 102313 N645 D N F I Y L Y N V S E N G R K
Zebra Danio Brachydanio rerio NP_001025406 805 88511 S644 D N F V Y I Y S V T E N G K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUI3 1076 119237 R914 I Y L F R V S R D G F S Y K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45487 891 98353 T729 G A T F A V A T K D P H L T I
Sea Urchin Strong. purpuratus Q26613 686 75435 S525 D N Y I Y I Y S V T E E G R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 78.7 97.3 N.A. 94.9 93.9 N.A. 51.8 54.4 41.7 57.6 N.A. 23.7 N.A. 23.5 53.9
Protein Similarity: 100 100 79.5 99 N.A. 97.6 97.2 N.A. 63.1 66.6 55.2 68.8 N.A. 35.8 N.A. 40.1 71.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 53.3 53.3 53.3 53.3 N.A. 20 N.A. 20 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 73.3 80 73.3 80 N.A. 26.6 N.A. 20 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 85 0 0 0 0 0 0 0 8 54 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 31 8 0 0 0 % E
% Phe: 0 0 16 16 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 16 0 8 0 47 85 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 0 0 31 0 31 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 0 16 93 % K
% Leu: 0 0 54 0 0 8 0 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 85 0 0 0 0 0 8 0 16 0 31 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 47 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 8 0 0 0 0 0 77 0 % R
% Ser: 0 0 8 0 0 0 8 16 0 8 0 8 0 0 0 % S
% Thr: 0 0 8 0 0 0 0 54 0 16 0 0 0 8 0 % T
% Val: 0 0 0 54 0 62 0 0 85 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 85 0 85 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _