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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EML2 All Species: 43.94
Human Site: T510 Identified Species: 80.56
UniProt: O95834 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95834 NP_036287.1 649 70679 T510 S G H S S F I T H L D W A Q D
Chimpanzee Pan troglodytes XP_001165936 649 70646 T510 S G H S S F I T H L D W A Q D
Rhesus Macaque Macaca mulatta XP_001110928 815 88569 T676 S G H S S F I T H L D W A Q D
Dog Lupus familis XP_852371 649 70597 T510 S G H S S F I T H L D W A Q D
Cat Felis silvestris
Mouse Mus musculus Q7TNG5 649 70715 T510 S G H S S F I T H L D W A Q D
Rat Rattus norvegicus Q6P6T4 649 70692 T510 S G H S S F I T H L D W A Q D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512831 860 95042 T721 S G H S S F I T H L D W S V N
Chicken Gallus gallus XP_421362 815 90017 T676 S G H S S F I T H L D W S V N
Frog Xenopus laevis Q2TAF3 927 102313 T667 T G H S S Y I T H L D W S P D
Zebra Danio Brachydanio rerio NP_001025406 805 88511 T666 T G H S S F V T H L D W S T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUI3 1076 119237 W936 Q P L T H L D W S M D G N F V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45487 891 98353 I751 N L L V I A R I H H I P A P I
Sea Urchin Strong. purpuratus Q26613 686 75435 T547 S G H S S F V T H I D W S A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 78.7 97.3 N.A. 94.9 93.9 N.A. 51.8 54.4 41.7 57.6 N.A. 23.7 N.A. 23.5 53.9
Protein Similarity: 100 100 79.5 99 N.A. 97.6 97.2 N.A. 63.1 66.6 55.2 68.8 N.A. 35.8 N.A. 40.1 71.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 80 80 73.3 73.3 N.A. 6.6 N.A. 13.3 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 93.3 93.3 N.A. 20 N.A. 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 0 0 54 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 93 0 0 0 70 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 77 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 85 0 0 0 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 85 0 8 0 0 0 93 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 70 8 0 8 8 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 16 0 0 8 0 0 0 77 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 16 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 8 0 16 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 47 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 70 0 0 85 85 0 0 0 8 0 0 0 39 0 0 % S
% Thr: 16 0 0 8 0 0 0 85 0 0 0 0 0 8 0 % T
% Val: 0 0 0 8 0 0 16 0 0 0 0 0 0 16 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 85 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _