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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML2
All Species:
41.21
Human Site:
Y487
Identified Species:
75.56
UniProt:
O95834
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95834
NP_036287.1
649
70679
Y487
H
D
N
L
V
Y
V
Y
T
V
D
Q
G
G
R
Chimpanzee
Pan troglodytes
XP_001165936
649
70646
Y487
H
D
N
L
V
Y
V
Y
T
V
D
Q
G
G
R
Rhesus Macaque
Macaca mulatta
XP_001110928
815
88569
Y653
H
D
N
L
V
Y
V
Y
T
V
D
Q
G
G
R
Dog
Lupus familis
XP_852371
649
70597
Y487
H
D
N
L
V
Y
V
Y
T
V
D
Q
G
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNG5
649
70715
Y487
H
D
N
L
V
Y
V
Y
T
V
D
Q
G
G
R
Rat
Rattus norvegicus
Q6P6T4
649
70692
Y487
H
D
N
L
V
Y
V
Y
T
V
D
Q
G
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
Y698
H
D
N
C
I
Y
I
Y
G
V
N
D
N
G
R
Chicken
Gallus gallus
XP_421362
815
90017
Y653
H
D
N
S
I
Y
I
Y
G
V
N
E
N
G
R
Frog
Xenopus laevis
Q2TAF3
927
102313
Y644
H
D
N
F
I
Y
L
Y
N
V
S
E
N
G
R
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
Y643
H
D
N
F
V
Y
I
Y
S
V
T
E
N
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
S913
S
I
Y
L
F
R
V
S
R
D
G
F
S
Y
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
A728
S
G
A
T
F
A
V
A
T
K
D
P
H
L
T
Sea Urchin
Strong. purpuratus
Q26613
686
75435
Y524
H
D
N
Y
I
Y
I
Y
S
V
T
E
E
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
78.7
97.3
N.A.
94.9
93.9
N.A.
51.8
54.4
41.7
57.6
N.A.
23.7
N.A.
23.5
53.9
Protein Similarity:
100
100
79.5
99
N.A.
97.6
97.2
N.A.
63.1
66.6
55.2
68.8
N.A.
35.8
N.A.
40.1
71.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
53.3
53.3
53.3
53.3
N.A.
13.3
N.A.
20
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
73.3
80
73.3
80
N.A.
20
N.A.
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
85
0
0
0
0
0
0
0
8
54
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
31
8
0
0
% E
% Phe:
0
0
0
16
16
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
16
0
8
0
47
85
0
% G
% His:
85
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
31
0
31
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
16
% K
% Leu:
0
0
0
54
0
0
8
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
85
0
0
0
0
0
8
0
16
0
31
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
77
% R
% Ser:
16
0
0
8
0
0
0
8
16
0
8
0
8
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
54
0
16
0
0
0
8
% T
% Val:
0
0
0
0
54
0
62
0
0
85
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
85
0
85
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _