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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML2
All Species:
44.24
Human Site:
Y61
Identified Species:
81.11
UniProt:
O95834
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95834
NP_036287.1
649
70679
Y61
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Chimpanzee
Pan troglodytes
XP_001165936
649
70646
Y61
R
L
K
L
D
W
V
Y
G
Y
R
G
R
D
C
Rhesus Macaque
Macaca mulatta
XP_001110928
815
88569
Y227
R
L
K
L
D
W
V
Y
G
Y
R
G
R
D
C
Dog
Lupus familis
XP_852371
649
70597
Y61
R
L
K
L
D
W
V
Y
G
Y
R
G
R
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNG5
649
70715
Y61
R
L
K
L
D
W
V
Y
G
Y
R
G
R
D
C
Rat
Rattus norvegicus
Q6P6T4
649
70692
Y61
R
L
K
L
D
W
V
Y
G
Y
R
G
R
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
Y272
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Chicken
Gallus gallus
XP_421362
815
90017
Y227
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Frog
Xenopus laevis
Q2TAF3
927
102313
F205
K
L
K
L
E
W
V
F
G
Y
R
G
R
D
C
Zebra Danio
Brachydanio rerio
NP_001025406
805
88511
Y217
K
L
K
L
Q
W
V
Y
G
Y
R
G
R
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUI3
1076
119237
H483
K
L
Q
L
Q
W
V
H
G
Y
R
G
I
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
Y286
K
V
T
L
K
H
V
Y
S
Y
R
G
K
D
V
Sea Urchin
Strong. purpuratus
Q26613
686
75435
Y100
K
L
K
L
D
W
V
Y
G
Y
R
G
R
D
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
78.7
97.3
N.A.
94.9
93.9
N.A.
51.8
54.4
41.7
57.6
N.A.
23.7
N.A.
23.5
53.9
Protein Similarity:
100
100
79.5
99
N.A.
97.6
97.2
N.A.
63.1
66.6
55.2
68.8
N.A.
35.8
N.A.
40.1
71.5
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
100
100
86.6
86.6
N.A.
60
N.A.
46.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
N.A.
73.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
85
% C
% Asp:
0
0
0
0
47
0
0
0
0
0
0
0
0
100
0
% D
% Glu:
0
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
93
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
39
0
85
0
8
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
93
0
100
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
16
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
62
0
0
0
0
0
0
0
0
0
100
0
85
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
100
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
93
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _