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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 24.85
Human Site: S1017 Identified Species: 39.05
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S1017 F K T I D F S S D L R Q Q S A
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S1017 F K T I D F S S D L R Q Q S A
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 T697 L T D F G L C T G F R W T H N
Dog Lupus familis XP_534537 1097 121903 G983 L K A H P F F G A I D F S S D
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 S1016 F K T I D F S S D L R Q Q S A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 S1007 F K V I D F S S D L R Q Q S A
Chicken Gallus gallus XP_419666 1136 127431 S1023 F K T I D F S S D L R R Q S A
Frog Xenopus laevis NP_001087838 1118 125984 S1003 F K S I D F S S D L R Q Q P A
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 L955 P F F R T I D L S K D L R Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 T993 A E L S R E A T D L I R R L C
Honey Bee Apis mellifera XP_395146 1137 124999 A1025 I L K L C V G A D R R L G K N
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529 R364 R F C C E A E R R L G N H G G
Sea Urchin Strong. purpuratus XP_795100 1199 133231 D1086 H P F F Q T I D L D S N I R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 D644 H I S Y E A E D L I R R L L T
Red Bread Mold Neurospora crassa P38679 598 67999 G486 F P D D I T L G V D A E N L I
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 6.6 20 N.A. 100 N.A. N.A. 93.3 93.3 86.6 0 N.A. 13.3 13.3 6.6 0
P-Site Similarity: 100 100 13.3 26.6 N.A. 100 N.A. N.A. 93.3 100 93.3 6.6 N.A. 46.6 26.6 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 14 7 7 7 0 7 0 0 0 40 % A
% Cys: 0 0 7 7 7 0 7 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 14 7 40 0 7 14 54 14 14 0 0 0 7 % D
% Glu: 0 7 0 0 14 7 14 0 0 0 0 7 0 0 0 % E
% Phe: 47 14 14 14 0 47 7 0 0 7 0 7 0 0 0 % F
% Gly: 0 0 0 0 7 0 7 14 7 0 7 0 7 7 7 % G
% His: 14 0 0 7 0 0 0 0 0 0 0 0 7 7 0 % H
% Ile: 7 7 0 40 7 7 7 0 0 14 7 0 7 0 7 % I
% Lys: 0 47 7 0 0 0 0 0 0 7 0 0 0 7 7 % K
% Leu: 14 7 7 7 0 7 7 7 14 54 0 14 7 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 14 7 0 14 % N
% Pro: 7 14 0 0 7 0 0 0 0 0 0 0 0 7 0 % P
% Gln: 0 0 0 0 7 0 0 0 0 0 0 34 40 7 7 % Q
% Arg: 7 0 0 7 7 0 0 7 7 7 60 20 14 7 0 % R
% Ser: 0 0 14 7 0 0 40 40 7 0 7 0 7 40 0 % S
% Thr: 0 7 27 0 7 14 0 14 0 0 0 0 7 0 7 % T
% Val: 0 0 7 0 0 7 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _