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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 14.55
Human Site: S1120 Identified Species: 22.86
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S1120 E D D Q N T G S E I K N R D L
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S1120 E D D Q N T G S E I K N R D L
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 T800 Q P P F L A P T P T E T Q L K
Dog Lupus familis XP_534537 1097 121903 V1086 D L E N S D M V D Q T E G C Q
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 S1119 E D D Q H T S S D G N N R D L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 T1110 E D G Q P T G T G V Q K I R D
Chicken Gallus gallus XP_419666 1136 127431 R1126 D D E E Q A G R G V Q N R D L
Frog Xenopus laevis NP_001087838 1118 125984 D1106 D A E E T E Q D G N R P L N R
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 P1058 E D E P S Q R P M E Q S R D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 M1096 D D K Q P P D M T D D Q A P V
Honey Bee Apis mellifera XP_395146 1137 124999 D1128 P S R I S L D D N D N Q G P V
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529 K467 F Q Q A K K N K K G G Q Q G T
Sea Urchin Strong. purpuratus XP_795100 1199 133231 S1189 G D G A A A Q S S L D M Q D M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 F747 I G Y T Y S R F D Y L T R K N
Red Bread Mold Neurospora crassa P38679 598 67999 T589 S L P F I G Y T F K R F D N N
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 0 0 N.A. 66.6 N.A. N.A. 33.3 40 0 33.3 N.A. 13.3 0 0 20
P-Site Similarity: 100 100 26.6 26.6 N.A. 80 N.A. N.A. 53.3 73.3 33.3 60 N.A. 26.6 13.3 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 14 7 20 0 0 0 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 27 54 20 0 0 7 14 14 20 14 14 0 7 40 7 % D
% Glu: 34 0 27 14 0 7 0 0 14 7 7 7 0 0 0 % E
% Phe: 7 0 0 14 0 0 0 7 7 0 0 7 0 0 0 % F
% Gly: 7 7 14 0 0 7 27 0 20 14 7 0 14 7 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 7 7 0 0 0 0 14 0 0 7 0 0 % I
% Lys: 0 0 7 0 7 7 0 7 7 7 14 7 0 7 7 % K
% Leu: 0 14 0 0 7 7 0 0 0 7 7 0 7 7 34 % L
% Met: 0 0 0 0 0 0 7 7 7 0 0 7 0 0 7 % M
% Asn: 0 0 0 7 14 0 7 0 7 7 14 27 0 14 14 % N
% Pro: 7 7 14 7 14 7 7 7 7 0 0 7 0 14 0 % P
% Gln: 7 7 7 34 7 7 14 0 0 7 20 20 20 0 7 % Q
% Arg: 0 0 7 0 0 0 14 7 0 0 14 0 40 7 7 % R
% Ser: 7 7 0 0 20 7 7 27 7 0 0 7 0 0 0 % S
% Thr: 0 0 0 7 7 27 0 20 7 7 7 14 0 0 7 % T
% Val: 0 0 0 0 0 0 0 7 0 14 0 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 7 0 7 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _