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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 10.91
Human Site: S184 Identified Species: 17.14
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S184 S W K G S K E S L V P Q R H G
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S184 S W K G S K E S L V P Q R H G
Rhesus Macaque Macaca mulatta XP_001090321 809 89257
Dog Lupus familis XP_534537 1097 121903 G171 V I K Q T S P G K G T V P A S
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 E183 Q S W K G S K E S L V P Q R H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 Q175 V P Q R L G P Q L G E N A V Y
Chicken Gallus gallus XP_419666 1136 127431 Q190 S K E S L V P Q R H G P S L A
Frog Xenopus laevis NP_001087838 1118 125984 S179 R R Q S W K G S K E S L I P Q
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 S170 S W K G S K E S L A P Q R H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 T173 T H Q P S S R T V G N P G G N
Honey Bee Apis mellifera XP_395146 1137 124999 Q220 P N V P T N M Q Q M L K R M S
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529
Sea Urchin Strong. purpuratus XP_795100 1199 133231 N260 Y V N P K R D N S G Y V S S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927
Red Bread Mold Neurospora crassa P38679 598 67999
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 0 6.6 N.A. 0 N.A. N.A. 6.6 6.6 13.3 86.6 N.A. 6.6 6.6 0 0
P-Site Similarity: 100 100 0 13.3 N.A. 20 N.A. N.A. 13.3 13.3 20 86.6 N.A. 33.3 26.6 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 7 0 0 7 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 0 0 0 20 7 0 7 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 20 7 7 7 7 0 27 7 0 7 7 14 % G
% His: 0 7 0 0 0 0 0 0 0 7 0 0 0 20 7 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 7 0 0 % I
% Lys: 0 7 27 7 7 27 7 0 14 0 0 7 0 0 0 % K
% Leu: 0 0 0 0 14 0 0 0 27 7 7 7 0 7 7 % L
% Met: 0 0 0 0 0 0 7 0 0 7 0 0 0 7 0 % M
% Asn: 0 7 7 0 0 7 0 7 0 0 7 7 0 0 7 % N
% Pro: 7 7 0 20 0 0 20 0 0 0 20 20 7 7 0 % P
% Gln: 7 0 20 7 0 0 0 20 7 0 0 20 7 0 7 % Q
% Arg: 7 7 0 7 0 7 7 0 7 0 0 0 27 7 0 % R
% Ser: 27 7 0 14 27 20 0 27 14 0 7 0 14 7 20 % S
% Thr: 7 0 0 0 14 0 0 7 0 0 7 0 0 0 0 % T
% Val: 14 7 7 0 0 7 0 0 7 14 7 14 0 7 0 % V
% Trp: 0 20 7 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _