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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 10.91
Human Site: S399 Identified Species: 17.14
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S399 G G S A A P S S Y T N G S I P
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S399 G G S A A P S S Y T N G N I P
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 P151 H L L V H G E P L G Y G V Q R
Dog Lupus familis XP_534537 1097 121903 R386 Q S S T L S R R D S L Q K P G
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 S398 G A S A A P P S F A N G N V P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 P390 G V P A A P S P Y A N G T V P
Chicken Gallus gallus XP_419666 1136 127431 A405 G G S A P P S A Y T N G N L P
Frog Xenopus laevis NP_001087838 1118 125984 Y394 G P L S S N A Y G T N T N L P
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 Q385 V I R P P V Q Q A Q T P P G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 P388 V L Q T A V A P Q S P S S A S
Honey Bee Apis mellifera XP_395146 1137 124999 P435 S T T S N T P P P P P S Y A S
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529
Sea Urchin Strong. purpuratus XP_795100 1199 133231 Q475 Q A G H I G G Q Q Q R G G T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 N98 P A T P P P H N N Y A A S N Q
Red Bread Mold Neurospora crassa P38679 598 67999
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 93.3 6.6 6.6 N.A. 60 N.A. N.A. 60 73.3 26.6 0 N.A. 13.3 0 0 13.3
P-Site Similarity: 100 100 6.6 13.3 N.A. 80 N.A. N.A. 73.3 93.3 60 0 N.A. 26.6 13.3 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 34 34 0 14 7 7 14 7 7 0 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 40 20 7 0 0 14 7 0 7 7 0 47 7 7 7 % G
% His: 7 0 0 7 7 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 7 0 0 0 0 0 0 0 0 14 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % K
% Leu: 0 14 14 0 7 0 0 0 7 0 7 0 0 14 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 7 0 7 7 0 40 0 27 7 0 % N
% Pro: 7 7 7 14 20 40 14 27 7 7 14 7 7 7 47 % P
% Gln: 14 0 7 0 0 0 7 14 14 14 0 7 0 7 14 % Q
% Arg: 0 0 7 0 0 0 7 7 0 0 7 0 0 0 7 % R
% Ser: 7 7 34 14 7 7 27 20 0 14 0 14 20 0 14 % S
% Thr: 0 7 14 14 0 7 0 0 0 27 7 7 7 7 0 % T
% Val: 14 7 0 7 0 14 0 0 0 0 0 0 7 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 27 7 7 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _