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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 22.42
Human Site: S464 Identified Species: 35.24
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S464 N I P V R S N S F N N P L G N
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S464 N I P V R S N S F N N P L G N
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 H216 G P T A H Q L H V L G S R S Q
Dog Lupus familis XP_534537 1097 121903 A451 N T I T A V T A A H I L H P V
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 S463 N I P V R S N S F N N P L G S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 S455 N I P V R S N S F N N P L G N
Chicken Gallus gallus XP_419666 1136 127431 S470 N L P A R S N S F N N H H G N
Frog Xenopus laevis NP_001087838 1118 125984 N459 P V R S N S F N N P V A S W Q
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 E450 S M R V Q K P E L H T A V A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 S453 P P L V G L N S K P N C L E P
Honey Bee Apis mellifera XP_395146 1137 124999 T500 G V S V G V P T T E P P S Y A
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529
Sea Urchin Strong. purpuratus XP_795100 1199 133231 T540 Q P Q P A V V T I S R I D P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 S163 N L N G S S S S S P F H Q P Q
Red Bread Mold Neurospora crassa P38679 598 67999
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 0 6.6 N.A. 93.3 N.A. N.A. 100 73.3 6.6 6.6 N.A. 33.3 13.3 0 6.6
P-Site Similarity: 100 100 0 20 N.A. 100 N.A. N.A. 100 80 20 40 N.A. 33.3 26.6 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 20 0
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 14 0 0 7 7 0 0 14 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % D
% Glu: 0 0 0 0 0 0 0 7 0 7 0 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 7 0 34 0 7 0 0 0 0 % F
% Gly: 14 0 0 7 14 0 0 0 0 0 7 0 0 34 0 % G
% His: 0 0 0 0 7 0 0 7 0 14 0 14 14 0 0 % H
% Ile: 0 27 7 0 0 0 0 0 7 0 7 7 0 0 0 % I
% Lys: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % K
% Leu: 0 14 7 0 0 7 7 0 7 7 0 7 34 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 47 0 7 0 7 0 40 7 7 34 40 0 0 0 34 % N
% Pro: 14 20 34 7 0 0 14 0 0 20 7 34 0 20 14 % P
% Gln: 7 0 7 0 7 7 0 0 0 0 0 0 7 0 20 % Q
% Arg: 0 0 14 0 34 0 0 0 0 0 7 0 7 0 0 % R
% Ser: 7 0 7 7 7 47 7 47 7 7 0 7 14 7 7 % S
% Thr: 0 7 7 7 0 0 7 14 7 0 7 0 0 0 0 % T
% Val: 0 14 0 47 0 20 7 0 7 0 7 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _