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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 13.03
Human Site: S476 Identified Species: 20.48
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S476 L G N R A S H S A N S Q P S A
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S476 L G N R A S H S A N S Q P S A
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 D228 R S Q V F A G D S P P Q S L L
Dog Lupus familis XP_534537 1097 121903 V463 H P V K S V R V M R P E P Q T
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 S475 L G S R A S H S A N S Q P S A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 P467 L G N R A S H P A S S Q P S A
Chicken Gallus gallus XP_419666 1136 127431 T482 H G N R Q S H T S S S Q P S A
Frog Xenopus laevis NP_001087838 1118 125984 N471 S W Q V L S N N A Q T S A T T
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 W462 V A P A H P P W L Q P P P P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 K465 L E P P S Y A K S M Q A K A A
Honey Bee Apis mellifera XP_395146 1137 124999 A512 S Y A T T M Q A L A A Q R G M
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529
Sea Urchin Strong. purpuratus XP_795100 1199 133231 G552 D P N N D L T G G S K P P P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 N175 Q P Q T L R S N G S Y S S G L
Red Bread Mold Neurospora crassa P38679 598 67999 R17 N L G T N D T R M A P N D R T
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 6.6 6.6 N.A. 93.3 N.A. N.A. 86.6 66.6 13.3 6.6 N.A. 13.3 6.6 0 13.3
P-Site Similarity: 100 100 20 26.6 N.A. 100 N.A. N.A. 93.3 86.6 40 13.3 N.A. 33.3 20 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 27 7 7 7 34 14 7 7 7 7 40 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 7 7 0 7 0 0 0 0 7 0 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 34 7 0 0 0 7 7 14 0 0 0 0 14 0 % G
% His: 14 0 0 0 7 0 34 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 0 0 0 7 0 0 7 0 7 0 0 % K
% Leu: 34 7 0 0 14 7 0 0 14 0 0 0 0 7 14 % L
% Met: 0 0 0 0 0 7 0 0 14 7 0 0 0 0 7 % M
% Asn: 7 0 34 7 7 0 7 14 0 20 0 7 0 0 0 % N
% Pro: 0 20 14 7 0 7 7 7 0 7 27 14 54 14 7 % P
% Gln: 7 0 20 0 7 0 7 0 0 14 7 47 0 7 0 % Q
% Arg: 7 0 0 34 0 7 7 7 0 7 0 0 7 7 0 % R
% Ser: 14 7 7 0 14 40 7 20 20 27 34 14 14 34 0 % S
% Thr: 0 0 0 20 7 0 14 7 0 0 7 0 0 7 27 % T
% Val: 7 0 7 14 0 7 0 7 0 0 0 0 0 0 0 % V
% Trp: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 7 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _