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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
16.06
Human Site:
S575
Identified Species:
25.24
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S575
P
S
V
P
P
Y
E
S
I
S
K
P
S
K
E
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S575
P
S
V
P
P
Y
E
S
I
S
K
S
S
K
E
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
I327
T
A
V
T
A
A
H
I
L
H
P
V
K
S
V
Dog
Lupus familis
XP_534537
1097
121903
K562
Q
A
A
E
P
A
D
K
T
D
K
S
H
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S574
P
S
V
P
P
Y
E
S
V
S
K
P
C
K
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
P566
P
S
V
P
P
Y
E
P
L
P
K
S
R
E
D
Chicken
Gallus gallus
XP_419666
1136
127431
T581
P
S
V
H
P
Y
E
T
G
A
K
L
S
K
E
Frog
Xenopus laevis
NP_001087838
1118
125984
A570
K
S
S
K
E
D
A
A
G
V
S
T
S
T
Q
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
R561
V
P
V
R
R
H
K
R
D
E
E
R
K
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
S564
N
S
E
I
K
P
P
S
C
N
N
N
N
I
Q
Honey Bee
Apis mellifera
XP_395146
1137
124999
G611
N
S
N
S
S
N
G
G
N
N
N
N
N
N
N
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
S651
T
Q
S
S
S
T
R
S
E
S
P
L
V
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
L274
Y
F
E
R
R
P
D
L
L
T
K
G
T
Q
D
Red Bread Mold
Neurospora crassa
P38679
598
67999
S116
Q
T
Y
G
N
Y
L
S
A
P
M
P
S
N
T
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
93.3
6.6
20
N.A.
80
N.A.
N.A.
53.3
66.6
13.3
13.3
N.A.
13.3
6.6
0
13.3
P-Site Similarity:
100
93.3
20
33.3
N.A.
93.3
N.A.
N.A.
73.3
80
26.6
33.3
N.A.
33.3
20
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
7
0
7
14
7
7
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% C
% Asp:
0
0
0
0
0
7
14
0
7
7
0
0
0
0
20
% D
% Glu:
0
0
14
7
7
0
34
0
7
7
7
0
0
7
27
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
7
7
14
0
0
7
0
7
0
% G
% His:
0
0
0
7
0
7
7
0
0
7
0
0
7
0
0
% H
% Ile:
0
0
0
7
0
0
0
7
14
0
0
0
0
7
0
% I
% Lys:
7
0
0
7
7
0
7
7
0
0
47
0
14
34
0
% K
% Leu:
0
0
0
0
0
0
7
7
20
0
0
14
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
14
0
7
0
7
7
0
0
7
14
14
14
14
14
7
% N
% Pro:
34
7
0
27
40
14
7
7
0
14
14
20
0
0
7
% P
% Gln:
14
7
0
0
0
0
0
0
0
0
0
0
0
7
14
% Q
% Arg:
0
0
0
14
14
0
7
7
0
0
0
7
7
7
0
% R
% Ser:
0
54
14
14
14
0
0
40
0
27
7
20
34
7
7
% S
% Thr:
14
7
0
7
0
7
0
7
7
7
0
7
7
7
7
% T
% Val:
7
0
47
0
0
0
0
0
7
7
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
40
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _