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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUCA1C
All Species:
16.97
Human Site:
T128
Identified Species:
31.11
UniProt:
O95843
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95843
NP_005450.3
209
23822
T128
Q
A
L
N
G
Q
Q
T
L
S
P
E
E
F
I
Chimpanzee
Pan troglodytes
XP_001174348
193
21804
T121
I
N
P
C
S
D
T
T
M
T
A
E
E
F
T
Rhesus Macaque
Macaca mulatta
XP_001102050
211
23861
T128
Q
A
L
N
G
Q
Q
T
L
S
P
E
E
F
T
Dog
Lupus familis
XP_545090
278
31616
T128
Q
A
L
N
G
Q
Q
T
L
S
P
E
E
F
T
Cat
Felis silvestris
Mouse
Mus musculus
P43081
202
22979
T121
T
I
I
R
A
I
R
T
I
N
P
W
S
D
S
Rat
Rattus norvegicus
P62749
193
22320
V125
R
S
E
M
L
E
I
V
Q
A
I
Y
K
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517475
188
21860
A120
N
I
I
K
A
I
R
A
I
N
G
C
E
H
E
Chicken
Gallus gallus
P79880
199
22789
A127
A
I
N
R
C
N
E
A
M
T
A
E
E
F
T
Frog
Xenopus laevis
Q7SY75
193
22246
V125
K
A
E
M
L
E
I
V
Q
A
I
Y
K
M
V
Zebra Danio
Brachydanio rerio
A9JTH1
193
22206
V125
K
S
E
M
L
E
I
V
Q
A
I
Y
K
M
V
Tiger Blowfish
Takifugu rubipres
NP_001027790
189
21769
A120
N
I
I
K
A
I
R
A
I
N
G
N
E
N
H
Fruit Fly
Dros. melanogaster
P42325
190
21875
Y115
Y
D
L
D
G
N
G
Y
I
S
R
Q
E
M
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P36609
190
21967
T117
Y
D
I
D
G
N
G
T
I
D
E
K
E
M
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.6
92.8
60
N.A.
44
26.7
N.A.
44.5
44.5
29.6
28.7
44
28.2
N.A.
27.7
N.A.
Protein Similarity:
100
64.1
95.7
68.3
N.A.
67.9
47.3
N.A.
63.6
71.2
48.3
48.7
64.1
44.5
N.A.
47.8
N.A.
P-Site Identity:
100
26.6
93.3
93.3
N.A.
13.3
0
N.A.
6.6
20
6.6
0
6.6
26.6
N.A.
26.6
N.A.
P-Site Similarity:
100
40
93.3
93.3
N.A.
40
40
N.A.
33.3
40
40
40
33.3
53.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
31
0
0
24
0
0
24
0
24
16
0
0
0
0
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
16
0
16
0
8
0
0
0
8
0
0
0
8
0
% D
% Glu:
0
0
24
0
0
24
8
0
0
0
8
39
70
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% F
% Gly:
0
0
0
0
39
0
16
0
0
0
16
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
8
31
31
0
0
24
24
0
39
0
24
0
0
0
16
% I
% Lys:
16
0
0
16
0
0
0
0
0
0
0
8
24
0
0
% K
% Leu:
0
0
31
0
24
0
0
0
24
0
0
0
0
0
8
% L
% Met:
0
0
0
24
0
0
0
0
16
0
0
0
0
39
0
% M
% Asn:
16
8
8
24
0
24
0
0
0
24
0
8
0
8
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
31
0
0
0
0
% P
% Gln:
24
0
0
0
0
24
24
0
24
0
0
8
0
0
0
% Q
% Arg:
8
0
0
16
0
0
24
0
0
0
8
0
0
0
0
% R
% Ser:
0
16
0
0
8
0
0
0
0
31
0
0
8
0
8
% S
% Thr:
8
0
0
0
0
0
8
47
0
16
0
0
0
0
31
% T
% Val:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
8
0
0
0
24
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _