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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GUCA1C All Species: 8.18
Human Site: Y30 Identified Species: 15
UniProt: O95843 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95843 NP_005450.3 209 23822 Y30 Y R T F M M E Y P S G L Q T L
Chimpanzee Pan troglodytes XP_001174348 193 21804 P30 K K F M T E C P S G Q L T L Y
Rhesus Macaque Macaca mulatta XP_001102050 211 23861 Y30 Y R T F M T E Y P S G L Q T L
Dog Lupus familis XP_545090 278 31616 Y30 Y R K F M R E Y P S G L Q T L
Cat Felis silvestris
Mouse Mus musculus P43081 202 22979 G32 F M T E V P S G Q L T L Y E F
Rat Rattus norvegicus P62749 193 22320 C38 Y K G F L K D C P T G H L T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517475 188 21860 G31 F M T E C P S G Q L T E H E F
Chicken Gallus gallus P79880 199 22789 G31 F M T E C P S G Q L T L Y E F
Frog Xenopus laevis Q7SY75 193 22246 C38 Y K G F L R D C P S G N L T M
Zebra Danio Brachydanio rerio A9JTH1 193 22206 C38 Y K G F L R D C P S G N L S M
Tiger Blowfish Takifugu rubipres NP_001027790 189 21769 G31 F M T E C P S G Q L T L H E F
Fruit Fly Dros. melanogaster P42325 190 21875 C38 Y K G F L K D C P S G H L S V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P36609 190 21967 C40 Y K G F V Q D C P K G H L T K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.6 92.8 60 N.A. 44 26.7 N.A. 44.5 44.5 29.6 28.7 44 28.2 N.A. 27.7 N.A.
Protein Similarity: 100 64.1 95.7 68.3 N.A. 67.9 47.3 N.A. 63.6 71.2 48.3 48.7 64.1 44.5 N.A. 47.8 N.A.
P-Site Identity: 100 6.6 93.3 86.6 N.A. 13.3 33.3 N.A. 6.6 13.3 40 33.3 13.3 33.3 N.A. 33.3 N.A.
P-Site Similarity: 100 13.3 93.3 86.6 N.A. 26.6 66.6 N.A. 13.3 20 66.6 66.6 20 66.6 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 24 0 8 39 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 39 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 31 0 8 24 0 0 0 0 8 0 31 0 % E
% Phe: 31 0 8 62 0 0 0 0 0 0 0 0 0 0 31 % F
% Gly: 0 0 39 0 0 0 0 31 0 8 62 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 24 16 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 47 8 0 0 16 0 0 0 8 0 0 0 0 8 % K
% Leu: 0 0 0 0 31 0 0 0 0 31 0 54 39 8 24 % L
% Met: 0 31 0 8 24 8 0 0 0 0 0 0 0 0 16 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % N
% Pro: 0 0 0 0 0 31 0 8 62 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 31 0 8 0 24 0 0 % Q
% Arg: 0 24 0 0 0 24 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 31 0 8 47 0 0 0 16 0 % S
% Thr: 0 0 47 0 8 8 0 0 0 8 31 0 8 47 0 % T
% Val: 0 0 0 0 16 0 0 0 0 0 0 0 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 62 0 0 0 0 0 0 24 0 0 0 0 16 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _