KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUCA1C
All Species:
25.45
Human Site:
Y96
Identified Species:
46.67
UniProt:
O95843
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95843
NP_005450.3
209
23822
Y96
M
E
Q
K
L
K
W
Y
F
K
L
Y
D
A
D
Chimpanzee
Pan troglodytes
XP_001174348
193
21804
R87
L
S
L
S
S
R
G
R
I
Q
L
Y
D
V
D
Rhesus Macaque
Macaca mulatta
XP_001102050
211
23861
Y96
M
E
Q
K
L
K
W
Y
F
K
L
Y
D
V
D
Dog
Lupus familis
XP_545090
278
31616
Y96
M
D
Q
K
L
K
W
Y
F
K
L
Y
D
A
D
Cat
Felis silvestris
Mouse
Mus musculus
P43081
202
22979
Y95
V
E
Q
K
L
R
W
Y
F
K
L
Y
D
V
D
Rat
Rattus norvegicus
P62749
193
22320
E98
V
T
S
R
G
K
L
E
Q
K
L
K
W
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517475
188
21860
Y94
M
E
Q
K
L
R
W
Y
F
K
L
Y
D
V
D
Chicken
Gallus gallus
P79880
199
22789
Y94
V
D
Q
K
L
R
W
Y
F
K
L
Y
D
V
D
Frog
Xenopus laevis
Q7SY75
193
22246
E98
V
T
S
R
G
K
L
E
Q
K
L
K
W
A
F
Zebra Danio
Brachydanio rerio
A9JTH1
193
22206
E98
V
T
S
R
G
K
L
E
Q
K
L
K
W
A
F
Tiger Blowfish
Takifugu rubipres
NP_001027790
189
21769
Y94
M
E
H
K
L
R
W
Y
F
K
L
Y
D
V
D
Fruit Fly
Dros. melanogaster
P42325
190
21875
L89
F
R
E
F
L
C
A
L
S
V
T
S
R
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P36609
190
21967
I91
F
K
E
F
L
L
A
I
N
V
T
S
S
G
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.6
92.8
60
N.A.
44
26.7
N.A.
44.5
44.5
29.6
28.7
44
28.2
N.A.
27.7
N.A.
Protein Similarity:
100
64.1
95.7
68.3
N.A.
67.9
47.3
N.A.
63.6
71.2
48.3
48.7
64.1
44.5
N.A.
47.8
N.A.
P-Site Identity:
100
26.6
93.3
93.3
N.A.
80
26.6
N.A.
86.6
73.3
26.6
26.6
80
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
46.6
93.3
100
N.A.
93.3
40
N.A.
93.3
93.3
40
40
86.6
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
0
0
0
0
0
0
39
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
0
0
0
0
0
0
0
62
0
62
% D
% Glu:
0
39
16
0
0
0
0
24
0
0
0
0
0
0
0
% E
% Phe:
16
0
0
16
0
0
0
0
54
0
0
0
0
0
24
% F
% Gly:
0
0
0
0
24
0
8
0
0
0
0
0
0
16
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
0
8
0
54
0
47
0
0
0
77
0
24
0
0
8
% K
% Leu:
8
0
8
0
70
8
24
8
0
0
85
0
0
0
0
% L
% Met:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
47
0
0
0
0
0
24
8
0
0
0
0
0
% Q
% Arg:
0
8
0
24
0
39
0
8
0
0
0
0
8
0
0
% R
% Ser:
0
8
24
8
8
0
0
0
8
0
0
16
8
0
0
% S
% Thr:
0
24
0
0
0
0
0
0
0
0
16
0
0
0
8
% T
% Val:
39
0
0
0
0
0
0
0
0
16
0
0
0
47
0
% V
% Trp:
0
0
0
0
0
0
54
0
0
0
0
0
24
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
62
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _