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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A27
All Species:
23.64
Human Site:
S272
Identified Species:
43.33
UniProt:
O95847
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95847
NP_004268.3
323
36064
S272
G
R
G
L
L
Y
K
S
S
T
D
C
L
I
Q
Chimpanzee
Pan troglodytes
XP_527398
323
36044
S272
G
R
G
L
L
Y
K
S
S
T
D
C
L
I
Q
Rhesus Macaque
Macaca mulatta
XP_001103050
322
35915
S271
G
R
G
L
L
Y
K
S
S
T
D
C
L
I
Q
Dog
Lupus familis
XP_852329
323
36032
S272
G
R
G
L
L
Y
K
S
S
T
D
C
L
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR58
291
32263
A233
T
R
M
M
N
Q
R
A
L
R
D
G
R
C
A
Rat
Rattus norvegicus
Q5PQM9
291
32346
G241
L
R
D
G
R
C
S
G
Y
K
G
T
L
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511667
321
35674
S270
G
R
G
L
L
Y
K
S
S
I
D
C
L
I
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GQ22
291
32540
D236
M
N
Q
R
S
I
R
D
A
S
N
S
S
Y
K
Zebra Danio
Brachydanio rerio
Q9W720
310
33554
S253
S
A
Q
G
Q
Y
S
S
A
L
N
C
A
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573246
340
37077
G289
G
R
G
L
L
Y
R
G
S
V
D
C
L
R
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505414
324
36554
G273
T
H
V
D
L
Y
K
G
V
V
D
C
Y
I
K
Sea Urchin
Strong. purpuratus
XP_785257
306
34356
S255
G
R
P
L
L
Y
K
S
S
M
D
C
L
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06143
298
32973
P244
N
G
S
G
D
H
Q
P
A
L
K
I
L
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
97.2
N.A.
37.7
38
N.A.
74.3
N.A.
35.2
32.5
N.A.
54.1
N.A.
47.8
60
Protein Similarity:
100
100
99.6
99.3
N.A.
57.2
57.5
N.A.
83.9
N.A.
56.3
53.5
N.A.
70.8
N.A.
66.6
76.1
P-Site Identity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
93.3
N.A.
0
20
N.A.
73.3
N.A.
40
73.3
P-Site Similarity:
100
100
100
100
N.A.
33.3
13.3
N.A.
93.3
N.A.
33.3
40
N.A.
80
N.A.
46.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
24
0
0
0
8
8
16
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
70
0
8
8
% C
% Asp:
0
0
8
8
8
0
0
8
0
0
70
0
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
54
8
47
24
0
0
0
24
0
0
8
8
0
0
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
0
8
0
39
0
% I
% Lys:
0
0
0
0
0
0
54
0
0
8
8
0
0
0
24
% K
% Leu:
8
0
0
54
62
0
0
0
8
16
0
0
70
8
0
% L
% Met:
8
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
8
0
0
8
0
0
0
0
0
16
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
16
0
8
8
8
0
0
0
0
0
0
0
47
% Q
% Arg:
0
70
0
8
8
0
24
0
0
8
0
0
8
8
0
% R
% Ser:
8
0
8
0
8
0
16
54
54
8
0
8
8
0
0
% S
% Thr:
16
0
0
0
0
0
0
0
0
31
0
8
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
8
16
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
70
0
0
8
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _