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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A27 All Species: 25.45
Human Site: S273 Identified Species: 46.67
UniProt: O95847 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95847 NP_004268.3 323 36064 S273 R G L L Y K S S T D C L I Q A
Chimpanzee Pan troglodytes XP_527398 323 36044 S273 R G L L Y K S S T D C L I Q A
Rhesus Macaque Macaca mulatta XP_001103050 322 35915 S272 R G L L Y K S S T D C L I Q A
Dog Lupus familis XP_852329 323 36032 S273 R G L L Y K S S T D C L V Q A
Cat Felis silvestris
Mouse Mus musculus Q9CR58 291 32263 L234 R M M N Q R A L R D G R C A G
Rat Rattus norvegicus Q5PQM9 291 32346 Y242 R D G R C S G Y K G T L D C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511667 321 35674 S271 R G L L Y K S S I D C L I Q T
Chicken Gallus gallus
Frog Xenopus laevis Q6GQ22 291 32540 A237 N Q R S I R D A S N S S Y K G
Zebra Danio Brachydanio rerio Q9W720 310 33554 A254 A Q G Q Y S S A L N C A V A M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573246 340 37077 S290 R G L L Y R G S V D C L R Q T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_505414 324 36554 V274 H V D L Y K G V V D C Y I K I
Sea Urchin Strong. purpuratus XP_785257 306 34356 S256 R P L L Y K S S M D C L L K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06143 298 32973 A245 G S G D H Q P A L K I L A D A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.3 97.2 N.A. 37.7 38 N.A. 74.3 N.A. 35.2 32.5 N.A. 54.1 N.A. 47.8 60
Protein Similarity: 100 100 99.6 99.3 N.A. 57.2 57.5 N.A. 83.9 N.A. 56.3 53.5 N.A. 70.8 N.A. 66.6 76.1
P-Site Identity: 100 100 100 93.3 N.A. 13.3 13.3 N.A. 86.6 N.A. 0 20 N.A. 66.6 N.A. 40 66.6
P-Site Similarity: 100 100 100 100 N.A. 33.3 13.3 N.A. 86.6 N.A. 33.3 40 N.A. 73.3 N.A. 46.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 8 24 0 0 0 8 8 16 39 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 70 0 8 8 0 % C
% Asp: 0 8 8 8 0 0 8 0 0 70 0 0 8 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 47 24 0 0 0 24 0 0 8 8 0 0 0 16 % G
% His: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 8 0 39 0 8 % I
% Lys: 0 0 0 0 0 54 0 0 8 8 0 0 0 24 0 % K
% Leu: 0 0 54 62 0 0 0 8 16 0 0 70 8 0 8 % L
% Met: 0 8 8 0 0 0 0 0 8 0 0 0 0 0 8 % M
% Asn: 8 0 0 8 0 0 0 0 0 16 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 16 0 8 8 8 0 0 0 0 0 0 0 47 0 % Q
% Arg: 70 0 8 8 0 24 0 0 8 0 0 8 8 0 0 % R
% Ser: 0 8 0 8 0 16 54 54 8 0 8 8 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 31 0 8 0 0 0 16 % T
% Val: 0 8 0 0 0 0 0 8 16 0 0 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 70 0 0 8 0 0 0 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _