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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A27
All Species:
22.73
Human Site:
S65
Identified Species:
41.67
UniProt:
O95847
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95847
NP_004268.3
323
36064
S65
L
G
D
G
A
R
E
S
A
P
Y
R
G
M
V
Chimpanzee
Pan troglodytes
XP_527398
323
36044
S65
L
G
D
G
A
R
E
S
A
P
Y
R
G
M
V
Rhesus Macaque
Macaca mulatta
XP_001103050
322
35915
S64
L
G
D
G
A
R
E
S
A
P
Y
R
G
M
V
Dog
Lupus familis
XP_852329
323
36032
S65
L
G
D
S
A
R
E
S
A
P
Y
R
G
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR58
291
32263
S70
E
G
L
K
A
L
Y
S
G
I
A
P
A
M
L
Rat
Rattus norvegicus
Q5PQM9
291
32346
S70
E
G
L
R
A
L
Y
S
G
I
A
P
A
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511667
321
35674
S63
Y
G
E
P
S
G
G
S
V
P
Y
R
G
M
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GQ22
291
32540
S70
E
G
V
K
A
L
Y
S
G
I
A
P
A
M
L
Zebra Danio
Brachydanio rerio
Q9W720
310
33554
Y60
M
G
R
G
P
V
K
Y
R
G
V
F
G
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573246
340
37077
N83
A
H
S
A
G
K
S
N
M
Q
Y
R
G
M
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505414
324
36554
K60
I
A
R
N
K
F
T
K
G
G
M
V
Q
V
T
Sea Urchin
Strong. purpuratus
XP_785257
306
34356
P76
K
L
W
Q
G
V
T
P
A
I
Y
R
H
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06143
298
32973
Q78
L
S
A
A
V
L
R
Q
C
T
Y
T
T
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
97.2
N.A.
37.7
38
N.A.
74.3
N.A.
35.2
32.5
N.A.
54.1
N.A.
47.8
60
Protein Similarity:
100
100
99.6
99.3
N.A.
57.2
57.5
N.A.
83.9
N.A.
56.3
53.5
N.A.
70.8
N.A.
66.6
76.1
P-Site Identity:
100
100
100
93.3
N.A.
26.6
26.6
N.A.
46.6
N.A.
26.6
20
N.A.
33.3
N.A.
0
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
33.3
N.A.
66.6
N.A.
33.3
40
N.A.
46.6
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
16
54
0
0
0
39
0
24
0
24
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
31
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
24
0
8
0
0
0
31
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
70
0
31
16
8
8
0
31
16
0
0
54
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
31
0
0
0
8
8
% I
% Lys:
8
0
0
16
8
8
8
8
0
0
0
0
0
0
0
% K
% Leu:
39
8
16
0
0
31
0
0
0
0
0
0
0
0
31
% L
% Met:
8
0
0
0
0
0
0
0
8
0
8
0
0
70
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
8
0
0
8
0
39
0
24
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
8
0
8
0
0
8
0
0
% Q
% Arg:
0
0
16
8
0
31
8
0
8
0
0
54
0
0
8
% R
% Ser:
0
8
8
8
8
0
8
62
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
16
0
0
8
0
8
8
8
8
% T
% Val:
0
0
8
0
8
16
0
0
8
0
8
8
0
16
47
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
24
8
0
0
62
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _