KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A27
All Species:
17.58
Human Site:
Y125
Identified Species:
32.22
UniProt:
O95847
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95847
NP_004268.3
323
36064
Y125
G
K
S
E
D
E
H
Y
P
L
W
K
S
V
I
Chimpanzee
Pan troglodytes
XP_527398
323
36044
Y125
G
K
S
E
D
E
H
Y
P
L
W
K
S
V
I
Rhesus Macaque
Macaca mulatta
XP_001103050
322
35915
Y124
G
K
S
E
D
E
H
Y
P
L
W
K
S
V
I
Dog
Lupus familis
XP_852329
323
36032
Y125
G
K
S
E
D
K
H
Y
P
L
W
K
S
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR58
291
32263
T127
S
S
A
I
A
N
P
T
D
V
L
K
I
R
M
Rat
Rattus norvegicus
Q5PQM9
291
32346
T127
S
S
A
I
A
N
P
T
D
V
L
K
I
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511667
321
35674
F123
G
K
S
E
D
K
H
F
P
L
W
K
A
V
M
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GQ22
291
32540
T127
S
S
C
I
A
N
P
T
D
V
L
K
I
R
M
Zebra Danio
Brachydanio rerio
Q9W720
310
33554
I117
K
G
S
D
H
A
G
I
G
S
R
L
M
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573246
340
37077
P143
Q
N
G
T
Q
A
L
P
V
W
K
S
A
L
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505414
324
36554
F117
N
K
E
V
E
K
S
F
P
L
W
K
S
M
L
Sea Urchin
Strong. purpuratus
XP_785257
306
34356
T140
L
V
K
V
Q
M
Q
T
E
G
R
R
R
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06143
298
32973
A138
I
R
M
Q
N
D
S
A
L
E
A
A
K
R
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
97.2
N.A.
37.7
38
N.A.
74.3
N.A.
35.2
32.5
N.A.
54.1
N.A.
47.8
60
Protein Similarity:
100
100
99.6
99.3
N.A.
57.2
57.5
N.A.
83.9
N.A.
56.3
53.5
N.A.
70.8
N.A.
66.6
76.1
P-Site Identity:
100
100
100
93.3
N.A.
6.6
6.6
N.A.
73.3
N.A.
6.6
6.6
N.A.
0
N.A.
40
0
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
100
N.A.
20
13.3
N.A.
13.3
N.A.
73.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
24
16
0
8
0
0
8
8
16
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
8
39
8
0
0
24
0
0
0
0
0
0
% D
% Glu:
0
0
8
39
8
24
0
0
8
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
39
8
8
0
0
0
8
0
8
8
0
0
0
0
8
% G
% His:
0
0
0
0
8
0
39
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
24
0
0
0
8
0
0
0
0
24
0
31
% I
% Lys:
8
47
8
0
0
24
0
0
0
0
8
70
8
0
0
% K
% Leu:
8
0
0
0
0
0
8
0
8
47
24
8
0
16
8
% L
% Met:
0
0
8
0
0
8
0
0
0
0
0
0
8
8
31
% M
% Asn:
8
8
0
0
8
24
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
24
8
47
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
16
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
16
8
8
31
8
% R
% Ser:
24
24
47
0
0
0
16
0
0
8
0
8
39
0
0
% S
% Thr:
0
0
0
8
0
0
0
31
0
0
0
0
0
0
0
% T
% Val:
0
8
0
16
0
0
0
0
8
24
0
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
47
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _