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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A27 All Species: 28.18
Human Site: Y270 Identified Species: 51.67
UniProt: O95847 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95847 NP_004268.3 323 36064 Y270 K Q G R G L L Y K S S T D C L
Chimpanzee Pan troglodytes XP_527398 323 36044 Y270 K Q G R G L L Y K S S T D C L
Rhesus Macaque Macaca mulatta XP_001103050 322 35915 Y269 K Q G R G L L Y K S S T D C L
Dog Lupus familis XP_852329 323 36032 Y270 K Q G R G L L Y K S S T D C L
Cat Felis silvestris
Mouse Mus musculus Q9CR58 291 32263 Q231 V R T R M M N Q R A L R D G R
Rat Rattus norvegicus Q5PQM9 291 32346 C239 R D L R D G R C S G Y K G T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511667 321 35674 Y268 K Q G R G L L Y K S S I D C L
Chicken Gallus gallus
Frog Xenopus laevis Q6GQ22 291 32540 I234 R M M N Q R S I R D A S N S S
Zebra Danio Brachydanio rerio Q9W720 310 33554 Y251 M N S A Q G Q Y S S A L N C A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573246 340 37077 Y287 E N G R G L L Y R G S V D C L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_505414 324 36554 Y271 K N T H V D L Y K G V V D C Y
Sea Urchin Strong. purpuratus XP_785257 306 34356 Y253 T S G R P L L Y K S S M D C L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06143 298 32973 H242 I M N G S G D H Q P A L K I L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.3 97.2 N.A. 37.7 38 N.A. 74.3 N.A. 35.2 32.5 N.A. 54.1 N.A. 47.8 60
Protein Similarity: 100 100 99.6 99.3 N.A. 57.2 57.5 N.A. 83.9 N.A. 56.3 53.5 N.A. 70.8 N.A. 66.6 76.1
P-Site Identity: 100 100 100 100 N.A. 13.3 13.3 N.A. 93.3 N.A. 0 20 N.A. 66.6 N.A. 40 73.3
P-Site Similarity: 100 100 100 100 N.A. 40 20 N.A. 93.3 N.A. 33.3 33.3 N.A. 80 N.A. 40 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 8 24 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 70 0 % C
% Asp: 0 8 0 0 8 8 8 0 0 8 0 0 70 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 54 8 47 24 0 0 0 24 0 0 8 8 0 % G
% His: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % I
% Lys: 47 0 0 0 0 0 0 0 54 0 0 8 8 0 0 % K
% Leu: 0 0 8 0 0 54 62 0 0 0 8 16 0 0 70 % L
% Met: 8 16 8 0 8 8 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 24 8 8 0 0 8 0 0 0 0 0 16 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 39 0 0 16 0 8 8 8 0 0 0 0 0 0 % Q
% Arg: 16 8 0 70 0 8 8 0 24 0 0 8 0 0 8 % R
% Ser: 0 8 8 0 8 0 8 0 16 54 54 8 0 8 8 % S
% Thr: 8 0 16 0 0 0 0 0 0 0 0 31 0 8 0 % T
% Val: 8 0 0 0 8 0 0 0 0 0 8 16 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 70 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _