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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FADS2 All Species: 26.67
Human Site: Y259 Identified Species: 73.33
UniProt: O95864 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95864 NP_004256.1 444 52259 Y259 K K L K Y L P Y N H Q H E Y F
Chimpanzee Pan troglodytes XP_508482 444 52271 Y259 K K L K Y L P Y N H Q H E Y F
Rhesus Macaque Macaca mulatta XP_001116616 386 45519 V201 N H L V H K F V I G H L K G A
Dog Lupus familis XP_540913 472 55572 Y287 K K L K Y L P Y N H Q H E Y F
Cat Felis silvestris
Mouse Mus musculus Q9Z0R9 444 52369 Y259 K K L K Y L P Y N H Q H E Y F
Rat Rattus norvegicus Q9Z122 444 52362 Y259 K K L K Y L P Y N H Q H E Y F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516455 374 43679 Q192 R Y L P Y N H Q H Q Y F F L I
Chicken Gallus gallus
Frog Xenopus laevis Q6DDK2 446 52296 Y261 K G I K Y L P Y N H Q H L Y F
Zebra Danio Brachydanio rerio Q9DEX7 444 52013 Y259 K K I K H L P Y N H Q H K Y F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 85.1 84.7 N.A. 87.6 88.2 N.A. 56.3 N.A. 71.3 64.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 86.2 90 N.A. 94.3 94.1 N.A. 67.5 N.A. 82.7 79.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 13.3 N.A. 80 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 26.6 N.A. 86.6 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 56 0 0 % E
% Phe: 0 0 0 0 0 0 12 0 0 0 0 12 12 0 78 % F
% Gly: 0 12 0 0 0 0 0 0 0 12 0 0 0 12 0 % G
% His: 0 12 0 0 23 0 12 0 12 78 12 78 0 0 0 % H
% Ile: 0 0 23 0 0 0 0 0 12 0 0 0 0 0 12 % I
% Lys: 78 67 0 78 0 12 0 0 0 0 0 0 23 0 0 % K
% Leu: 0 0 78 0 0 78 0 0 0 0 0 12 12 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 12 0 0 78 0 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 0 78 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 12 0 12 78 0 0 0 0 % Q
% Arg: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 12 0 0 0 12 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 78 0 0 78 0 0 12 0 0 78 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _