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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC12
All Species:
22.12
Human Site:
S121
Identified Species:
48.67
UniProt:
O95881
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95881
NP_056997.1
172
19206
S121
R
I
L
F
L
D
P
S
G
K
V
H
P
E
I
Chimpanzee
Pan troglodytes
XP_001149873
166
19169
F121
Q
Y
V
P
R
I
M
F
V
D
P
S
L
T
V
Rhesus Macaque
Macaca mulatta
XP_001110583
172
19229
S121
R
I
L
F
L
D
P
S
G
K
V
H
P
E
I
Dog
Lupus familis
XP_852280
172
19028
S121
R
I
L
F
L
D
P
S
G
K
V
H
P
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQU0
170
19030
S119
R
I
L
F
L
D
P
S
G
K
V
R
P
E
I
Rat
Rattus norvegicus
Q498E0
170
19000
S119
R
I
L
F
L
D
P
S
G
K
V
R
P
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509609
235
25330
S140
R
I
L
F
M
D
P
S
G
K
V
H
P
E
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZZH4
164
18665
V120
Y
V
P
K
I
I
F
V
D
P
S
L
V
V
R
Zebra Danio
Brachydanio rerio
Q5RZ65
171
19658
F126
Q
Y
V
P
R
I
I
F
V
D
P
S
M
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508381
257
30186
D120
R
I
L
F
L
D
T
D
G
N
P
L
K
T
N
Sea Urchin
Strong. purpuratus
XP_791682
161
17742
D116
R
I
L
F
L
N
S
D
G
V
V
Q
P
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.7
98.8
94.7
N.A.
90.6
90.1
N.A.
45.5
N.A.
31.9
34.2
N.A.
N.A.
N.A.
28.7
50.5
Protein Similarity:
100
51.1
100
95.3
N.A.
94.1
93.5
N.A.
51.9
N.A.
52.3
48.2
N.A.
N.A.
N.A.
38.1
66.2
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
0
0
N.A.
N.A.
N.A.
46.6
53.3
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
100
N.A.
13.3
20
N.A.
N.A.
N.A.
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
64
0
19
10
19
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% E
% Phe:
0
0
0
73
0
0
10
19
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
37
0
0
0
% H
% Ile:
0
73
0
0
10
28
10
0
0
0
0
0
0
0
55
% I
% Lys:
0
0
0
10
0
0
0
0
0
55
0
0
10
0
0
% K
% Leu:
0
0
73
0
64
0
0
0
0
0
0
19
10
0
10
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% N
% Pro:
0
0
10
19
0
0
55
0
0
10
28
0
64
0
0
% P
% Gln:
19
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
73
0
0
0
19
0
0
0
0
0
0
19
0
0
10
% R
% Ser:
0
0
0
0
0
0
10
55
0
0
10
19
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
28
0
% T
% Val:
0
10
19
0
0
0
0
10
19
10
64
0
10
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _