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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECD
All Species:
27.27
Human Site:
S205
Identified Species:
50
UniProt:
O95905
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95905
NP_001129225.1
644
72758
S205
Y
P
E
K
I
Q
A
S
L
H
R
A
H
C
F
Chimpanzee
Pan troglodytes
XP_508169
648
72940
S205
Y
P
E
K
I
Q
A
S
L
H
R
A
H
C
F
Rhesus Macaque
Macaca mulatta
XP_001103459
644
72818
S205
Y
P
E
K
I
Q
V
S
L
H
R
A
H
C
F
Dog
Lupus familis
XP_536386
643
72587
S205
Y
P
E
K
I
Q
A
S
L
H
R
A
H
C
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CS74
641
71691
S205
Y
P
E
R
V
E
A
S
L
H
R
A
H
C
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508376
598
66758
K185
S
E
K
I
L
A
A
K
S
I
Q
V
A
I
N
Chicken
Gallus gallus
XP_421522
638
71575
S201
Y
P
E
K
I
Q
A
S
Y
H
R
A
H
C
Y
Frog
Xenopus laevis
NP_001088274
642
71779
S204
Y
P
E
K
I
K
D
S
L
H
R
A
H
S
F
Zebra Danio
Brachydanio rerio
XP_002665219
632
70256
N204
Y
P
D
K
I
Q
Q
N
V
H
R
A
H
C
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W032
684
77889
F225
Y
Q
I
A
Q
P
H
F
S
I
H
R
Q
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786801
567
62710
S162
K
L
P
S
P
T
S
S
K
F
K
S
A
D
L
Poplar Tree
Populus trichocarpa
XP_002326322
639
72489
N197
Y
P
E
R
A
R
R
N
M
H
Q
A
R
V
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LSM5
643
73143
N203
Y
P
E
R
A
W
R
N
M
H
R
V
R
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
95.9
86.6
N.A.
78.4
N.A.
N.A.
59.4
59.3
60
52.6
N.A.
29.6
N.A.
N.A.
21.2
Protein Similarity:
100
97.3
97.9
92.6
N.A.
89.1
N.A.
N.A.
73.1
72.9
75.6
69.8
N.A.
49.5
N.A.
N.A.
36.6
P-Site Identity:
100
100
93.3
100
N.A.
80
N.A.
N.A.
6.6
86.6
80
66.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
26.6
93.3
86.6
93.3
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
34
N.A.
N.A.
35.4
N.A.
N.A.
Protein Similarity:
55.2
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
16
8
47
0
0
0
0
70
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
0
% C
% Asp:
0
0
8
0
0
0
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
70
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
47
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
77
8
0
62
0
0
% H
% Ile:
0
0
8
8
54
0
0
0
0
16
0
0
0
8
0
% I
% Lys:
8
0
8
54
0
8
0
8
8
0
8
0
0
0
0
% K
% Leu:
0
8
0
0
8
0
0
0
47
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
8
% N
% Pro:
0
77
8
0
8
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
47
8
0
0
0
16
0
8
0
0
% Q
% Arg:
0
0
0
24
0
8
16
0
0
0
70
8
16
0
16
% R
% Ser:
8
0
0
8
0
0
8
62
16
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
8
0
8
0
0
16
0
24
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
85
0
0
0
0
0
0
0
8
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _