KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECD
All Species:
30.91
Human Site:
S419
Identified Species:
56.67
UniProt:
O95905
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95905
NP_001129225.1
644
72758
S419
D
D
Q
W
L
D
L
S
P
D
Q
L
D
Q
L
Chimpanzee
Pan troglodytes
XP_508169
648
72940
S423
D
D
Q
W
L
D
L
S
P
D
Q
L
D
Q
L
Rhesus Macaque
Macaca mulatta
XP_001103459
644
72818
S419
D
D
Q
W
L
D
L
S
P
D
Q
L
D
Q
L
Dog
Lupus familis
XP_536386
643
72587
S419
D
D
Q
W
L
A
L
S
P
D
Q
L
D
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CS74
641
71691
S419
D
D
Q
W
L
D
L
S
P
D
Q
L
D
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508376
598
66758
S369
A
E
S
Y
F
Q
Q
S
V
D
R
P
D
S
S
Chicken
Gallus gallus
XP_421522
638
71575
T414
D
D
S
W
L
E
I
T
P
D
A
L
D
Q
M
Frog
Xenopus laevis
NP_001088274
642
71779
S417
D
D
S
W
L
D
L
S
P
E
S
L
E
K
I
Zebra Danio
Brachydanio rerio
XP_002665219
632
70256
P406
K
K
Q
E
A
N
L
P
P
E
D
S
D
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W032
684
77889
S438
S
D
E
W
L
N
I
S
A
E
D
L
D
S
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786801
567
62710
E345
E
V
D
F
D
P
G
E
V
T
E
S
L
K
S
Poplar Tree
Populus trichocarpa
XP_002326322
639
72489
P397
F
S
C
Q
E
V
P
P
S
D
D
D
S
W
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LSM5
643
73143
G412
N
D
S
W
L
Y
D
G
E
D
E
L
N
S
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
95.9
86.6
N.A.
78.4
N.A.
N.A.
59.4
59.3
60
52.6
N.A.
29.6
N.A.
N.A.
21.2
Protein Similarity:
100
97.3
97.9
92.6
N.A.
89.1
N.A.
N.A.
73.1
72.9
75.6
69.8
N.A.
49.5
N.A.
N.A.
36.6
P-Site Identity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
20
60
60
26.6
N.A.
40
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
40
86.6
86.6
40
N.A.
73.3
N.A.
N.A.
26.6
Percent
Protein Identity:
34
N.A.
N.A.
35.4
N.A.
N.A.
Protein Similarity:
55.2
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
0
0
8
0
8
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
70
8
0
8
39
8
0
0
70
24
8
70
0
0
% D
% Glu:
8
8
8
8
8
8
0
8
8
24
16
0
8
0
0
% E
% Phe:
8
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
8
% I
% Lys:
8
8
0
0
0
0
0
0
0
0
0
0
0
16
0
% K
% Leu:
0
0
0
0
70
0
54
0
0
0
0
70
8
0
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% M
% Asn:
8
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
8
8
16
62
0
0
8
0
0
0
% P
% Gln:
0
0
47
8
0
8
8
0
0
0
39
0
0
47
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
8
31
0
0
0
0
62
8
0
8
16
8
24
16
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
8
0
0
0
8
0
0
16
0
0
0
0
0
8
% V
% Trp:
0
0
0
70
0
0
0
0
0
0
0
0
0
8
8
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _