KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECD
All Species:
16.67
Human Site:
S579
Identified Species:
30.56
UniProt:
O95905
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95905
NP_001129225.1
644
72758
S579
S
Q
T
T
D
N
N
S
D
E
E
D
S
G
T
Chimpanzee
Pan troglodytes
XP_508169
648
72940
S583
S
Q
T
T
D
N
N
S
D
E
E
D
S
G
T
Rhesus Macaque
Macaca mulatta
XP_001103459
644
72818
S579
S
Q
T
T
D
N
N
S
D
Q
E
D
S
D
T
Dog
Lupus familis
XP_536386
643
72587
S578
S
Q
T
T
N
N
N
S
D
E
E
D
S
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CS74
641
71691
D577
P
P
S
H
T
A
N
D
N
S
D
E
E
D
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508376
598
66758
N533
A
R
G
Q
L
A
Q
N
P
D
I
D
S
D
D
Chicken
Gallus gallus
XP_421522
638
71575
N573
A
K
A
A
P
S
Q
N
A
G
L
G
S
E
E
Frog
Xenopus laevis
NP_001088274
642
71779
S577
G
A
Q
S
A
E
D
S
S
S
E
E
D
T
A
Zebra Danio
Brachydanio rerio
XP_002665219
632
70256
S564
S
F
T
Q
N
N
R
S
S
N
K
A
E
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W032
684
77889
Q618
G
K
K
K
T
A
P
Q
A
D
E
D
D
F
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786801
567
62710
R503
P
S
H
S
T
T
G
R
D
N
H
Q
E
L
R
Poplar Tree
Populus trichocarpa
XP_002326322
639
72489
L555
M
N
T
Y
S
D
A
L
N
E
E
L
K
N
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LSM5
643
73143
N575
E
K
S
F
E
N
V
N
Q
Q
H
S
S
K
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
95.9
86.6
N.A.
78.4
N.A.
N.A.
59.4
59.3
60
52.6
N.A.
29.6
N.A.
N.A.
21.2
Protein Similarity:
100
97.3
97.9
92.6
N.A.
89.1
N.A.
N.A.
73.1
72.9
75.6
69.8
N.A.
49.5
N.A.
N.A.
36.6
P-Site Identity:
100
100
86.6
86.6
N.A.
6.6
N.A.
N.A.
13.3
6.6
13.3
26.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
40
N.A.
N.A.
40
33.3
33.3
46.6
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
34
N.A.
N.A.
35.4
N.A.
N.A.
Protein Similarity:
55.2
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
8
8
24
8
0
16
0
0
8
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
24
8
8
8
39
16
8
47
16
24
16
% D
% Glu:
8
0
0
0
8
8
0
0
0
31
54
16
24
8
8
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
16
0
8
0
0
0
8
0
0
8
0
8
0
24
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
16
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
24
8
8
0
0
0
0
0
0
8
0
8
8
0
% K
% Leu:
0
0
0
0
8
0
0
8
0
0
8
8
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
16
47
39
24
16
16
0
0
0
8
0
% N
% Pro:
16
8
0
0
8
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
31
8
16
0
0
16
8
8
16
0
8
0
0
8
% Q
% Arg:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
8
% R
% Ser:
39
8
16
16
8
8
0
47
16
16
0
8
54
0
16
% S
% Thr:
0
0
47
31
24
8
0
0
0
0
0
0
0
8
31
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _