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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC16A8 All Species: 10
Human Site: S443 Identified Species: 24.44
UniProt: O95907 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95907 NP_037488.2 504 52319 S443 R C A K A A P S G P G T E G G
Chimpanzee Pan troglodytes XP_001163402 504 52316 S443 R C A K A A P S G P G T E G G
Rhesus Macaque Macaca mulatta XP_001092182 510 52692 A449 R C A K A A P A G P G T E G G
Dog Lupus familis XP_540498 470 50429 L415 V L V L G N F L C I R K R P E
Cat Felis silvestris
Mouse Mus musculus O35308 492 51538 S419 R C S K N I S S G R S A E G G
Rat Rattus norvegicus O70461 492 51572 S419 R C S K N I S S G R S A E G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519725 787 84186 P720 R P A E E P L P P P E L Q P P
Chicken Gallus gallus Q90632 542 58161 P456 N R G K K T P P P E K N P S A
Frog Xenopus laevis Q6GM59 460 50319 L395 S P P I A G W L V D T T G D Y
Zebra Danio Brachydanio rerio Q503M4 477 51835 I421 F L S G F A L I S S S L L L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 93.7 55.5 N.A. 84.7 84.5 N.A. 43.3 59.4 31.7 30.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 95.4 67 N.A. 86.9 86.5 N.A. 49.6 72.8 46.6 48.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 0 N.A. 53.3 53.3 N.A. 20 13.3 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 60 60 N.A. 33.3 13.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 40 0 40 40 0 10 0 0 0 20 0 0 10 % A
% Cys: 0 50 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % D
% Glu: 0 0 0 10 10 0 0 0 0 10 10 0 50 0 10 % E
% Phe: 10 0 0 0 10 0 10 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 10 10 10 10 0 0 50 0 30 0 10 50 50 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 20 0 10 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 60 10 0 0 0 0 0 10 10 0 0 0 % K
% Leu: 0 20 0 10 0 0 20 20 0 0 0 20 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 20 10 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 20 10 0 0 10 40 20 20 40 0 0 10 20 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 60 10 0 0 0 0 0 0 0 20 10 0 10 0 0 % R
% Ser: 10 0 30 0 0 0 20 40 10 10 30 0 0 10 0 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 10 40 0 0 0 % T
% Val: 10 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _