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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC16A8
All Species:
14.85
Human Site:
S452
Identified Species:
36.3
UniProt:
O95907
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95907
NP_037488.2
504
52319
S452
P
G
T
E
G
G
A
S
D
T
E
D
A
E
A
Chimpanzee
Pan troglodytes
XP_001163402
504
52316
S452
P
G
T
E
G
G
A
S
D
T
E
D
T
E
A
Rhesus Macaque
Macaca mulatta
XP_001092182
510
52692
S458
P
G
T
E
G
G
A
S
D
T
E
D
A
E
A
Dog
Lupus familis
XP_540498
470
50429
V424
I
R
K
R
P
E
V
V
A
A
V
A
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
O35308
492
51538
S428
R
S
A
E
G
G
A
S
D
P
E
D
V
E
A
Rat
Rattus norvegicus
O70461
492
51572
S428
R
S
A
E
G
G
A
S
D
P
E
D
V
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519725
787
84186
P729
P
E
L
Q
P
P
A
P
R
G
D
S
D
T
E
Chicken
Gallus gallus
Q90632
542
58161
G465
E
K
N
P
S
A
G
G
G
S
D
T
E
E
A
Frog
Xenopus laevis
Q6GM59
460
50319
A404
D
T
T
G
D
Y
T
A
A
F
L
L
S
G
F
Zebra Danio
Brachydanio rerio
Q503M4
477
51835
V430
S
S
L
L
L
F
S
V
A
I
I
R
Y
C
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
93.7
55.5
N.A.
84.7
84.5
N.A.
43.3
59.4
31.7
30.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
95.4
67
N.A.
86.9
86.5
N.A.
49.6
72.8
46.6
48.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
6.6
N.A.
66.6
66.6
N.A.
13.3
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
6.6
N.A.
66.6
66.6
N.A.
26.6
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
10
60
10
30
10
0
10
20
0
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
0
0
10
0
0
0
50
0
20
50
10
0
0
% D
% Glu:
10
10
0
50
0
10
0
0
0
0
50
0
20
70
20
% E
% Phe:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% F
% Gly:
0
30
0
10
50
50
10
10
10
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% I
% Lys:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
20
10
10
0
0
0
0
0
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
40
0
0
10
20
10
0
10
0
20
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
20
10
0
10
0
0
0
0
10
0
0
10
0
0
0
% R
% Ser:
10
30
0
0
10
0
10
50
0
10
0
10
10
0
0
% S
% Thr:
0
10
40
0
0
0
10
0
0
30
0
10
10
10
0
% T
% Val:
0
0
0
0
0
0
10
20
0
0
10
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _