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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYF2 All Species: 39.09
Human Site: S166 Identified Species: 66.15
UniProt: O95926 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95926 NP_056299.1 243 28722 S166 E F F P T S N S L L H G T H V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113990 156 18386 K86 L Q E E E K K K E C A S R G E
Dog Lupus familis XP_535357 315 36880 S238 E F F P T S N S L L H G T H V
Cat Felis silvestris
Mouse Mus musculus Q9D198 242 28694 S165 D F F P T S N S L L H G T H V
Rat Rattus norvegicus NP_596908 242 28770 S165 D F F P T S N S L L H G T H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510962 278 32257 S201 D F Y P T S D S L L H G T H V
Chicken Gallus gallus XP_417740 386 43430 S309 A L Y P T S D S L L H G T H V
Frog Xenopus laevis Q8AVQ6 240 28458 S163 L F Y P T S D S L Y H G T H V
Zebra Danio Brachydanio rerio Q6DGP2 238 28290 S161 D F H P T S N S L I Y G T H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V5Q4 226 26518 T149 A F Y G G A H T T L H S R T K
Honey Bee Apis mellifera XP_394026 230 27345 T153 A F Y G D K N T I L H G L H E
Nematode Worm Caenorhab. elegans Q09385 234 27641 D156 E Q F Y P T A D T L I H G N H
Sea Urchin Strong. purpuratus XP_788894 252 29915 T175 D I Y P D Q D T L T Q V D F K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RZK5 339 37943 S260 T F F S T A D S T Q F A Q H K
Conservation
Percent
Protein Identity: 100 N.A. 61.7 73.3 N.A. 90.9 90.5 N.A. 75.5 55.4 81 77.3 N.A. 53.9 56.7 47.3 57.5
Protein Similarity: 100 N.A. 64.1 75.8 N.A. 94.2 93.8 N.A. 81.6 59 86.4 86.4 N.A. 69.1 72 71.5 75.4
P-Site Identity: 100 N.A. 0 100 N.A. 93.3 93.3 N.A. 80 73.3 73.3 73.3 N.A. 20 40 20 13.3
P-Site Similarity: 100 N.A. 0 100 N.A. 100 100 N.A. 100 86.6 86.6 93.3 N.A. 46.6 60 33.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.2
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 41
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 0 0 15 8 0 0 0 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 36 0 0 0 15 0 36 8 0 0 0 0 8 0 0 % D
% Glu: 22 0 8 8 8 0 0 0 8 0 0 0 0 0 15 % E
% Phe: 0 72 43 0 0 0 0 0 0 0 8 0 0 8 0 % F
% Gly: 0 0 0 15 8 0 0 0 0 0 0 65 8 8 0 % G
% His: 0 0 8 0 0 0 8 0 0 0 65 8 0 72 8 % H
% Ile: 0 8 0 0 0 0 0 0 8 8 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 15 8 8 0 0 0 0 0 0 22 % K
% Leu: 15 8 0 0 0 0 0 0 65 65 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 43 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 65 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 15 0 0 0 8 0 0 0 8 8 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % R
% Ser: 0 0 0 8 0 58 0 65 0 0 0 15 0 0 0 % S
% Thr: 8 0 0 0 65 8 0 22 22 8 0 0 58 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 58 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 43 8 0 0 0 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _