KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYF2
All Species:
24.55
Human Site:
S175
Identified Species:
41.54
UniProt:
O95926
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95926
NP_056299.1
243
28722
S175
L
H
G
T
H
V
P
S
T
E
E
I
D
R
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113990
156
18386
Y95
C
A
S
R
G
E
D
Y
E
K
V
K
L
L
E
Dog
Lupus familis
XP_535357
315
36880
S247
L
H
G
T
H
V
P
S
T
E
E
V
D
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9D198
242
28694
S174
L
H
G
T
H
V
P
S
S
E
E
I
D
R
M
Rat
Rattus norvegicus
NP_596908
242
28770
F174
L
H
G
T
H
V
P
F
S
E
E
I
D
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510962
278
32257
S210
L
H
G
T
H
V
P
S
Q
E
G
I
D
R
M
Chicken
Gallus gallus
XP_417740
386
43430
D318
L
H
G
T
H
V
P
D
K
E
G
I
D
R
M
Frog
Xenopus laevis
Q8AVQ6
240
28458
S172
Y
H
G
T
H
V
P
S
Q
S
G
I
D
R
M
Zebra Danio
Brachydanio rerio
Q6DGP2
238
28290
S170
I
Y
G
T
H
V
P
S
K
D
S
I
N
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Q4
226
26518
T158
L
H
S
R
T
K
D
T
P
G
A
I
N
K
M
Honey Bee
Apis mellifera
XP_394026
230
27345
K162
L
H
G
L
H
E
D
K
K
E
A
I
D
K
M
Nematode Worm
Caenorhab. elegans
Q09385
234
27641
P165
L
I
H
G
N
H
Y
P
T
T
A
A
M
D
K
Sea Urchin
Strong. purpuratus
XP_788894
252
29915
T184
T
Q
V
D
F
K
D
T
E
E
G
I
N
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RZK5
339
37943
D269
Q
F
A
Q
H
K
P
D
K
A
A
V
D
R
L
Conservation
Percent
Protein Identity:
100
N.A.
61.7
73.3
N.A.
90.9
90.5
N.A.
75.5
55.4
81
77.3
N.A.
53.9
56.7
47.3
57.5
Protein Similarity:
100
N.A.
64.1
75.8
N.A.
94.2
93.8
N.A.
81.6
59
86.4
86.4
N.A.
69.1
72
71.5
75.4
P-Site Identity:
100
N.A.
0
93.3
N.A.
93.3
86.6
N.A.
86.6
80
73.3
60
N.A.
26.6
53.3
13.3
26.6
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
93.3
N.A.
86.6
80
73.3
86.6
N.A.
46.6
60
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
8
29
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
29
15
0
8
0
0
65
8
0
% D
% Glu:
0
0
0
0
0
15
0
0
15
58
29
0
0
0
8
% E
% Phe:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
65
8
8
0
0
0
0
8
29
0
0
0
0
% G
% His:
0
65
8
0
72
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
72
0
0
0
% I
% Lys:
0
0
0
0
0
22
0
8
29
8
0
8
0
15
8
% K
% Leu:
65
0
0
8
0
0
0
0
0
0
0
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
79
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
22
0
0
% N
% Pro:
0
0
0
0
0
0
65
8
8
0
0
0
0
0
0
% P
% Gln:
8
8
0
8
0
0
0
0
15
0
0
0
0
0
0
% Q
% Arg:
0
0
0
15
0
0
0
0
0
0
0
0
0
72
0
% R
% Ser:
0
0
15
0
0
0
0
43
15
8
8
0
0
0
0
% S
% Thr:
8
0
0
58
8
0
0
15
22
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
58
0
0
0
0
8
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _