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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYF2 All Species: 43.03
Human Site: S197 Identified Species: 72.82
UniProt: O95926 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95926 NP_056299.1 243 28722 S197 I E K R D K Y S R R R P Y N D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113990 156 18386 E112 A E D A E K W E R K K K R K N
Dog Lupus familis XP_535357 315 36880 S269 I E K R D K Y S R R R P Y N D
Cat Felis silvestris
Mouse Mus musculus Q9D198 242 28694 S196 I E K R D K Y S R R R P Y N D
Rat Rattus norvegicus NP_596908 242 28770 S196 I E K R D K Y S R R R P Y N D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510962 278 32257 S232 I E K R E K Y S R R R P Y N D
Chicken Gallus gallus XP_417740 386 43430 S340 I E K R E K Y S R R R P Y N D
Frog Xenopus laevis Q8AVQ6 240 28458 S194 I E K R E K Y S R R R A Y N D
Zebra Danio Brachydanio rerio Q6DGP2 238 28290 S192 I E K R A K Y S R R R A Y N D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V5Q4 226 26518 S180 I E R R K K Y S R R R I Y N D
Honey Bee Apis mellifera XP_394026 230 27345 S184 I A K R D K Y S R R R M H N D
Nematode Worm Caenorhab. elegans Q09385 234 27641 H188 V K R R E Q Y H R R R L Y D P
Sea Urchin Strong. purpuratus XP_788894 252 29915 S206 I E K R N K Y S R R R A F N E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RZK5 339 37943 E293 A S L K K R R E R M A N N G D
Conservation
Percent
Protein Identity: 100 N.A. 61.7 73.3 N.A. 90.9 90.5 N.A. 75.5 55.4 81 77.3 N.A. 53.9 56.7 47.3 57.5
Protein Similarity: 100 N.A. 64.1 75.8 N.A. 94.2 93.8 N.A. 81.6 59 86.4 86.4 N.A. 69.1 72 71.5 75.4
P-Site Identity: 100 N.A. 20 100 N.A. 100 100 N.A. 93.3 93.3 86.6 86.6 N.A. 80 80 40 73.3
P-Site Similarity: 100 N.A. 53.3 100 N.A. 100 100 N.A. 100 100 93.3 86.6 N.A. 86.6 86.6 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.2
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 41
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 8 8 0 0 0 0 0 8 22 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 36 0 0 0 0 0 0 0 0 8 79 % D
% Glu: 0 79 0 0 36 0 0 15 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % H
% Ile: 79 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 8 72 8 15 86 0 0 0 8 8 8 0 8 0 % K
% Leu: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 8 8 79 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 43 0 0 8 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 15 86 0 8 8 0 100 86 86 0 8 0 0 % R
% Ser: 0 8 0 0 0 0 0 79 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 86 0 0 0 0 0 72 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _