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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYF2
All Species:
46.97
Human Site:
Y196
Identified Species:
79.49
UniProt:
O95926
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95926
NP_056299.1
243
28722
Y196
Q
I
E
K
R
D
K
Y
S
R
R
R
P
Y
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113990
156
18386
W111
S
A
E
D
A
E
K
W
E
R
K
K
K
R
K
Dog
Lupus familis
XP_535357
315
36880
Y268
Q
I
E
K
R
D
K
Y
S
R
R
R
P
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D198
242
28694
Y195
Q
I
E
K
R
D
K
Y
S
R
R
R
P
Y
N
Rat
Rattus norvegicus
NP_596908
242
28770
Y195
Q
I
E
K
R
D
K
Y
S
R
R
R
P
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510962
278
32257
Y231
Q
I
E
K
R
E
K
Y
S
R
R
R
P
Y
N
Chicken
Gallus gallus
XP_417740
386
43430
Y339
Q
I
E
K
R
E
K
Y
S
R
R
R
P
Y
N
Frog
Xenopus laevis
Q8AVQ6
240
28458
Y193
Q
I
E
K
R
E
K
Y
S
R
R
R
A
Y
N
Zebra Danio
Brachydanio rerio
Q6DGP2
238
28290
Y191
Q
I
E
K
R
A
K
Y
S
R
R
R
A
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Q4
226
26518
Y179
Q
I
E
R
R
K
K
Y
S
R
R
R
I
Y
N
Honey Bee
Apis mellifera
XP_394026
230
27345
Y183
Q
I
A
K
R
D
K
Y
S
R
R
R
M
H
N
Nematode Worm
Caenorhab. elegans
Q09385
234
27641
Y187
Q
V
K
R
R
E
Q
Y
H
R
R
R
L
Y
D
Sea Urchin
Strong. purpuratus
XP_788894
252
29915
Y205
Q
I
E
K
R
N
K
Y
S
R
R
R
A
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RZK5
339
37943
R292
E
A
S
L
K
K
R
R
E
R
M
A
N
N
G
Conservation
Percent
Protein Identity:
100
N.A.
61.7
73.3
N.A.
90.9
90.5
N.A.
75.5
55.4
81
77.3
N.A.
53.9
56.7
47.3
57.5
Protein Similarity:
100
N.A.
64.1
75.8
N.A.
94.2
93.8
N.A.
81.6
59
86.4
86.4
N.A.
69.1
72
71.5
75.4
P-Site Identity:
100
N.A.
20
100
N.A.
100
100
N.A.
93.3
93.3
86.6
86.6
N.A.
80
80
46.6
80
P-Site Similarity:
100
N.A.
46.6
100
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
86.6
86.6
86.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
0
8
8
0
0
0
0
0
8
22
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
36
0
0
0
0
0
0
0
0
8
% D
% Glu:
8
0
79
0
0
36
0
0
15
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
79
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
8
72
8
15
86
0
0
0
8
8
8
0
8
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
79
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
43
0
0
% P
% Gln:
86
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
15
86
0
8
8
0
100
86
86
0
8
0
% R
% Ser:
8
0
8
0
0
0
0
0
79
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
72
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _