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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYF2
All Species:
51.21
Human Site:
Y226
Identified Species:
86.67
UniProt:
O95926
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95926
NP_056299.1
243
28722
Y226
N
K
K
A
E
R
F
Y
G
K
Y
T
A
E
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113990
156
18386
K140
R
Q
Y
H
R
L
T
K
Q
I
K
P
D
M
E
Dog
Lupus familis
XP_535357
315
36880
Y298
N
K
K
A
E
R
F
Y
G
K
Y
T
A
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D198
242
28694
Y225
N
K
K
A
E
R
F
Y
G
K
Y
T
A
E
I
Rat
Rattus norvegicus
NP_596908
242
28770
Y225
N
K
K
A
E
R
F
Y
G
K
Y
T
A
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510962
278
32257
Y261
N
K
K
A
E
R
F
Y
G
K
Y
T
A
E
I
Chicken
Gallus gallus
XP_417740
386
43430
Y369
N
K
K
A
E
R
F
Y
G
K
Y
T
A
E
I
Frog
Xenopus laevis
Q8AVQ6
240
28458
Y223
N
K
K
A
E
R
F
Y
G
K
Y
T
A
E
I
Zebra Danio
Brachydanio rerio
Q6DGP2
238
28290
Y221
N
K
K
A
E
R
F
Y
G
K
Y
T
A
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Q4
226
26518
Y209
N
K
K
L
D
R
F
Y
S
E
H
T
A
E
I
Honey Bee
Apis mellifera
XP_394026
230
27345
Y213
N
Q
K
L
E
R
F
Y
G
E
Y
T
R
E
T
Nematode Worm
Caenorhab. elegans
Q09385
234
27641
Y217
N
K
K
L
D
K
Y
Y
G
K
Y
T
E
D
I
Sea Urchin
Strong. purpuratus
XP_788894
252
29915
Y235
N
K
K
I
E
R
F
Y
G
K
Y
T
A
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RZK5
339
37943
Y322
N
Q
K
L
S
R
F
Y
N
K
Y
T
A
E
I
Conservation
Percent
Protein Identity:
100
N.A.
61.7
73.3
N.A.
90.9
90.5
N.A.
75.5
55.4
81
77.3
N.A.
53.9
56.7
47.3
57.5
Protein Similarity:
100
N.A.
64.1
75.8
N.A.
94.2
93.8
N.A.
81.6
59
86.4
86.4
N.A.
69.1
72
71.5
75.4
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
66.6
66.6
60
93.3
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
80
86.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
58
0
0
0
0
0
0
0
0
79
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
0
0
0
0
72
0
0
0
0
15
0
0
8
86
8
% E
% Phe:
0
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
79
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
86
% I
% Lys:
0
79
93
0
0
8
0
8
0
79
8
0
0
0
0
% K
% Leu:
0
0
0
29
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
93
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
22
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
86
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
93
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
93
0
0
86
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _