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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBX18 All Species: 22.73
Human Site: S216 Identified Species: 50
UniProt: O95935 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95935 NP_001073977.1 607 64753 S216 M V A G N A D S P V P P R V Y
Chimpanzee Pan troglodytes XP_530953 607 64762 S216 M V A G N A D S P V P P R V Y
Rhesus Macaque Macaca mulatta XP_001086401 607 64685 S216 M V A G N A D S P V P P R V Y
Dog Lupus familis XP_539024 1238 133036 S847 M V A G N A D S P V P P R V Y
Cat Felis silvestris
Mouse Mus musculus Q9EPZ6 613 65445 S222 M V A G N A D S P V P P R V Y
Rat Rattus norvegicus Q5I2P1 517 57726 P129 S V T G K A E P A M P G R L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509854 596 63747 S205 M V A G N A D S P V P P R V Y
Chicken Gallus gallus Q8UW76 440 48669 C51 Q F V E K S S C A Q P L S D L
Frog Xenopus laevis Q8AXW8 441 48933 Q53 V E K S S C S Q P I G D I S I
Zebra Danio Brachydanio rerio Q9I9K7 446 49284 L58 C H P N L G D L P P L E T H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90971 346 39417
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.3 47.9 N.A. 93.4 27.8 N.A. 82.8 35.9 34.2 34.7 N.A. N.A. N.A. 28.8 N.A.
Protein Similarity: 100 99.8 99.3 48.1 N.A. 94.2 40.5 N.A. 87.4 47.1 47.4 47.7 N.A. N.A. N.A. 39.8 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 40 N.A. 100 6.6 6.6 13.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 60 N.A. 100 13.3 26.6 13.3 N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 55 0 0 64 0 0 19 0 0 0 0 0 0 % A
% Cys: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 64 0 0 0 0 10 0 10 0 % D
% Glu: 0 10 0 10 0 0 10 0 0 0 0 10 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 64 0 10 0 0 0 0 10 10 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 10 % I
% Lys: 0 0 10 0 19 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 10 0 0 10 10 0 10 10 % L
% Met: 55 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 10 55 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 10 73 10 73 55 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 64 0 0 % R
% Ser: 10 0 0 10 10 10 19 55 0 0 0 0 10 10 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 10 64 10 0 0 0 0 0 0 55 0 0 0 55 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _