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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX18
All Species:
22.73
Human Site:
S282
Identified Species:
50
UniProt:
O95935
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95935
NP_001073977.1
607
64753
S282
K
D
C
G
D
D
L
S
P
I
K
P
V
P
S
Chimpanzee
Pan troglodytes
XP_530953
607
64762
S282
K
D
C
G
D
D
L
S
P
I
K
P
V
P
S
Rhesus Macaque
Macaca mulatta
XP_001086401
607
64685
S282
K
D
C
G
D
D
L
S
P
I
K
P
V
P
S
Dog
Lupus familis
XP_539024
1238
133036
S913
K
D
C
G
D
D
L
S
P
I
K
P
V
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPZ6
613
65445
S288
K
D
C
G
D
D
L
S
P
I
K
P
V
P
S
Rat
Rattus norvegicus
Q5I2P1
517
57726
F194
K
A
D
E
N
N
G
F
G
S
K
N
T
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509854
596
63747
S271
K
D
C
G
D
D
L
S
P
V
K
P
I
P
S
Chicken
Gallus gallus
Q8UW76
440
48669
I116
E
L
G
T
E
M
I
I
T
K
S
G
R
R
M
Frog
Xenopus laevis
Q8AXW8
441
48933
K118
G
T
E
M
I
I
T
K
S
G
R
R
M
F
P
Zebra Danio
Brachydanio rerio
Q9I9K7
446
49284
K123
G
T
E
M
I
I
T
K
S
G
R
R
M
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90971
346
39417
F22
E
P
V
K
K
P
R
F
S
I
A
N
I
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.3
47.9
N.A.
93.4
27.8
N.A.
82.8
35.9
34.2
34.7
N.A.
N.A.
N.A.
28.8
N.A.
Protein Similarity:
100
99.8
99.3
48.1
N.A.
94.2
40.5
N.A.
87.4
47.1
47.4
47.7
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
86.6
0
0
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
20
13.3
13.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
10
0
0
10
0
% A
% Cys:
0
0
55
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
55
10
0
55
55
0
0
0
0
0
0
0
0
10
% D
% Glu:
19
0
19
10
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
0
0
0
0
19
10
% F
% Gly:
19
0
10
55
0
0
10
0
10
19
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
19
19
10
10
0
55
0
0
19
0
0
% I
% Lys:
64
0
0
10
10
0
0
19
0
10
64
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
55
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
19
0
10
0
0
0
0
0
0
19
0
10
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
0
19
0
0
0
% N
% Pro:
0
10
0
0
0
10
0
0
55
0
0
55
0
55
19
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
19
19
10
10
0
% R
% Ser:
0
0
0
0
0
0
0
55
28
10
10
0
0
0
55
% S
% Thr:
0
19
0
10
0
0
19
0
10
0
0
0
10
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
10
0
0
46
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _