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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EOMES All Species: 20
Human Site: S138 Identified Species: 36.67
UniProt: O95936 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95936 NP_005433.2 686 72732 S138 T A R Y S M D S L S S E R Y Y
Chimpanzee Pan troglodytes XP_001165803 690 73333 S142 T A R Y S M D S L S S E R Y Y
Rhesus Macaque Macaca mulatta XP_001093085 737 80029 S171 T A R Y S M D S L S S E R Y Y
Dog Lupus familis XP_850738 688 72729 S140 T A R Y S M D S L S S E R Y Y
Cat Felis silvestris
Mouse Mus musculus O54839 707 74783 S140 T A R Y S M D S L S S E R Y Y
Rat Rattus norvegicus XP_001061749 663 70857 Y137 T A A A T A R Y S M D S L S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514679 386 42515
Chicken Gallus gallus XP_426003 399 44936
Frog Xenopus laevis P79944 692 75925 R136 A V P T S A P R Y L D G S L Q
Zebra Danio Brachydanio rerio NP_571754 661 71990 S136 P Y G G Q T G S V Y S G S N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 A201 P S H H P T A A H H S P S T G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979
Sea Urchin Strong. purpuratus XP_791266 946 105128 L250 C S N T D D K L S T S A N H N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 80 96.5 N.A. 87.5 81.6 N.A. 25.6 52.4 62.1 57.5 N.A. 22.9 N.A. 24.7 23.6
Protein Similarity: 100 99.1 82.9 96.9 N.A. 89.3 83.9 N.A. 33.5 54.5 70.5 68.9 N.A. 35.2 N.A. 34.9 37.9
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 0 0 6.6 13.3 N.A. 6.6 N.A. 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 0 0 6.6 20 N.A. 26.6 N.A. 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 47 8 8 0 16 8 8 0 0 0 8 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 39 0 0 0 16 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 39 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 0 0 8 0 0 0 0 16 0 0 16 % G
% His: 0 0 8 8 0 0 0 0 8 8 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 8 39 8 0 0 8 8 0 % L
% Met: 0 0 0 0 0 39 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 8 8 8 % N
% Pro: 16 0 8 0 8 0 8 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 39 0 0 0 8 8 0 0 0 0 39 0 0 % R
% Ser: 0 16 0 0 47 0 0 47 16 39 62 8 24 8 8 % S
% Thr: 47 0 0 16 8 16 0 0 0 8 0 0 0 8 0 % T
% Val: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 39 0 0 0 8 8 8 0 0 0 39 39 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _