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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EOMES
All Species:
22.42
Human Site:
T421
Identified Species:
41.11
UniProt:
O95936
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95936
NP_005433.2
686
72732
T421
N
E
P
S
K
T
Q
T
F
T
F
S
E
T
Q
Chimpanzee
Pan troglodytes
XP_001165803
690
73333
T425
N
E
P
S
K
T
Q
T
F
T
F
S
E
T
Q
Rhesus Macaque
Macaca mulatta
XP_001093085
737
80029
T453
N
E
P
S
K
T
Q
T
F
T
F
S
E
T
Q
Dog
Lupus familis
XP_850738
688
72729
T423
N
E
P
S
K
T
Q
T
F
T
F
S
E
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
O54839
707
74783
T423
N
E
P
S
K
T
Q
T
F
T
F
S
E
T
Q
Rat
Rattus norvegicus
XP_001061749
663
70857
Q400
Y
Q
N
T
D
I
T
Q
L
K
I
D
H
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514679
386
42515
T124
E
T
P
C
P
S
P
T
S
H
T
F
S
F
I
Chicken
Gallus gallus
XP_426003
399
44936
I137
S
S
K
T
Q
T
F
I
F
P
E
T
Q
F
I
Frog
Xenopus laevis
P79944
692
75925
T408
N
D
S
A
K
N
Q
T
F
T
F
P
E
N
Q
Zebra Danio
Brachydanio rerio
NP_571754
661
71990
D399
P
F
A
K
G
F
R
D
N
Y
D
S
M
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
F481
S
T
F
R
T
Y
V
F
K
E
T
E
F
I
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
G159
G
E
H
W
M
S
K
G
A
N
F
H
K
L
K
Sea Urchin
Strong. purpuratus
XP_791266
946
105128
V522
P
E
T
Q
F
F
G
V
T
A
Y
Q
N
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80
96.5
N.A.
87.5
81.6
N.A.
25.6
52.4
62.1
57.5
N.A.
22.9
N.A.
24.7
23.6
Protein Similarity:
100
99.1
82.9
96.9
N.A.
89.3
83.9
N.A.
33.5
54.5
70.5
68.9
N.A.
35.2
N.A.
34.9
37.9
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
13.3
13.3
60
6.6
N.A.
0
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
20
46.6
73.3
13.3
N.A.
6.6
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
8
8
0
0
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
8
0
0
8
8
0
0
8
% D
% Glu:
8
54
0
0
0
0
0
0
0
8
8
8
47
0
0
% E
% Phe:
0
8
8
0
8
16
8
8
54
0
54
8
8
16
0
% F
% Gly:
8
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
8
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
8
0
0
8
16
% I
% Lys:
0
0
8
8
47
0
8
0
8
8
0
0
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
47
0
8
0
0
8
0
0
8
8
0
0
8
16
0
% N
% Pro:
16
0
47
0
8
0
8
0
0
8
0
8
0
0
8
% P
% Gln:
0
8
0
8
8
0
47
8
0
0
0
8
8
0
47
% Q
% Arg:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
16
8
8
39
0
16
0
0
8
0
0
47
8
0
0
% S
% Thr:
0
16
8
16
8
47
8
54
8
47
16
8
0
47
8
% T
% Val:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
8
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _