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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX6
All Species:
16.67
Human Site:
S303
Identified Species:
30.56
UniProt:
O95947
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95947
NP_004599.2
436
47045
S303
A
A
T
E
A
Y
G
S
G
D
T
P
G
G
P
Chimpanzee
Pan troglodytes
XP_523337
436
47083
S303
A
A
A
E
A
Y
G
S
G
D
T
P
G
G
P
Rhesus Macaque
Macaca mulatta
XP_001098963
496
53657
S312
A
Q
P
L
P
S
L
S
P
D
A
P
G
G
P
Dog
Lupus familis
XP_547068
436
47185
S303
I
A
A
E
A
Y
G
S
G
D
P
P
G
G
P
Cat
Felis silvestris
Mouse
Mus musculus
P70327
540
58610
S303
V
A
T
E
A
C
G
S
G
D
T
P
G
G
P
Rat
Rattus norvegicus
Q5I2P1
517
57726
Y379
A
Q
R
Q
A
C
M
Y
A
S
S
A
P
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520749
277
31432
P153
V
Y
I
H
P
D
S
P
A
T
G
A
H
W
M
Chicken
Gallus gallus
P79779
361
41167
E237
G
Q
K
R
K
L
P
E
E
K
E
S
G
A
E
Frog
Xenopus laevis
Q8AV66
506
56540
D286
D
G
M
K
S
K
R
D
R
S
I
R
G
K
R
Zebra Danio
Brachydanio rerio
P79742
473
53459
P283
S
S
S
V
S
L
N
P
F
I
S
A
F
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
A553
A
P
L
H
L
G
H
A
G
R
P
P
H
L
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
K296
E
P
T
L
K
K
C
K
P
E
P
S
Q
T
P
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
T397
S
G
S
Q
L
T
C
T
S
P
D
N
G
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
81.8
90.1
N.A.
64.4
34.8
N.A.
43.8
35
43
37
N.A.
22.8
N.A.
35.5
30.2
Protein Similarity:
100
99
83.2
92.1
N.A.
67.9
48.5
N.A.
48.3
47.4
54.5
52.8
N.A.
30.7
N.A.
52.5
43.8
P-Site Identity:
100
93.3
46.6
80
N.A.
86.6
13.3
N.A.
0
6.6
6.6
0
N.A.
20
N.A.
13.3
6.6
P-Site Similarity:
100
93.3
46.6
80
N.A.
86.6
26.6
N.A.
0
6.6
20
33.3
N.A.
26.6
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
31
16
0
39
0
0
8
16
0
8
24
0
8
0
% A
% Cys:
0
0
0
0
0
16
16
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
8
0
39
8
0
0
0
0
% D
% Glu:
8
0
0
31
0
0
0
8
8
8
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% F
% Gly:
8
16
0
0
0
8
31
0
39
0
8
0
62
39
8
% G
% His:
0
0
0
16
0
0
8
0
0
0
0
0
16
0
8
% H
% Ile:
8
0
8
0
0
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
0
8
8
16
16
0
8
0
8
0
0
0
8
0
% K
% Leu:
0
0
8
16
16
16
8
0
0
0
0
0
0
8
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% N
% Pro:
0
16
8
0
16
0
8
16
16
8
24
47
8
8
47
% P
% Gln:
0
24
0
16
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
8
8
0
0
8
0
8
8
0
8
0
0
8
% R
% Ser:
16
8
16
0
16
8
8
39
8
16
16
16
0
0
8
% S
% Thr:
0
0
24
0
0
8
0
8
0
8
24
0
0
16
0
% T
% Val:
16
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
24
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _