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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBX6 All Species: 18.18
Human Site: S92 Identified Species: 33.33
UniProt: O95947 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95947 NP_004599.2 436 47045 S92 L H S L P G V S L S L E N R E
Chimpanzee Pan troglodytes XP_523337 436 47083 S92 L H S L P G V S L S L E N R E
Rhesus Macaque Macaca mulatta XP_001098963 496 53657 S92 L H S L P G V S L S L E N R E
Dog Lupus familis XP_547068 436 47185 S92 L H S L P G V S L S L D N R E
Cat Felis silvestris
Mouse Mus musculus P70327 540 58610 S92 L H S L P G V S L S L E N Q E
Rat Rattus norvegicus Q5I2P1 517 57726 G193 V K A D E N N G F G S K N T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520749 277 31432
Chicken Gallus gallus P79779 361 41167 K51 G T E M I I T K S G R R M F P
Frog Xenopus laevis Q8AV66 506 56540 K97 P Q L P G N V K M K L E N K E
Zebra Danio Brachydanio rerio P79742 473 53459 N91 M D M V P F D N H K Y K W N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 K329 D G V V D D P K V T L E G K D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979 G100 A Y R V K I S G L D K K S Q Y
Sea Urchin Strong. purpuratus XP_797010 645 70075 K138 N P A T K D I K V T L E G R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 81.8 90.1 N.A. 64.4 34.8 N.A. 43.8 35 43 37 N.A. 22.8 N.A. 35.5 30.2
Protein Similarity: 100 99 83.2 92.1 N.A. 67.9 48.5 N.A. 48.3 47.4 54.5 52.8 N.A. 30.7 N.A. 52.5 43.8
P-Site Identity: 100 100 100 93.3 N.A. 93.3 6.6 N.A. 0 0 33.3 6.6 N.A. 13.3 N.A. 6.6 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 0 6.6 46.6 40 N.A. 46.6 N.A. 40 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 0 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 8 16 8 0 0 8 0 8 0 0 8 % D
% Glu: 0 0 8 0 8 0 0 0 0 0 0 54 0 0 54 % E
% Phe: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 0 % F
% Gly: 8 8 0 0 8 39 0 16 0 16 0 0 16 0 0 % G
% His: 0 39 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 16 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 16 0 0 31 0 16 8 24 0 16 8 % K
% Leu: 39 0 8 39 0 0 0 0 47 0 62 0 0 0 0 % L
% Met: 8 0 8 8 0 0 0 0 8 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 0 16 8 8 0 0 0 0 54 8 0 % N
% Pro: 8 8 0 8 47 0 8 0 0 0 0 0 0 0 8 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 16 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 8 8 0 39 0 % R
% Ser: 0 0 39 0 0 0 8 39 8 39 8 0 8 0 0 % S
% Thr: 0 8 0 8 0 0 8 0 0 16 0 0 0 8 0 % T
% Val: 8 0 8 24 0 0 47 0 16 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _