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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ONECUT2 All Species: 15.15
Human Site: S145 Identified Species: 33.33
UniProt: O95948 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95948 NP_004843.2 504 54303 S145 S P P G M G M S N T Y T T L T
Chimpanzee Pan troglodytes XP_523935 499 54831 S140 S P P G M G M S N T Y T T L T
Rhesus Macaque Macaca mulatta XP_001087035 1137 121923 S777 S P P G M G M S N T Y T T L T
Dog Lupus familis XP_541087 307 34190
Cat Felis silvestris
Mouse Mus musculus Q6XBJ3 505 54536 S144 S P P G M G M S N T Y T T L T
Rat Rattus norvegicus P70512 465 51049 H124 T V S D K F P H H H H H H H H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510495 398 44524 K57 P I S T V S D K F H P H P H P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002661005 441 48471 I100 P L Q H L P P I S T V S D K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NJB5 1081 117679 Q333 L S S P G F S Q T S Y A T L T
Honey Bee Apis mellifera XP_624996 770 74637 A385 S V A S M I D A T D F R A M Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999824 483 51431 S136 T N V S T G F S L M N S S N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.7 43.7 59.7 N.A. 98.6 61.3 N.A. 69.4 N.A. N.A. 62.2 N.A. 25 31.6 N.A. 42.8
Protein Similarity: 100 79.9 44 60.3 N.A. 98.8 70.6 N.A. 72.4 N.A. N.A. 70.8 N.A. 33.1 39 N.A. 52.7
P-Site Identity: 100 100 100 0 N.A. 100 0 N.A. 0 N.A. N.A. 6.6 N.A. 26.6 13.3 N.A. 13.3
P-Site Similarity: 100 100 100 0 N.A. 100 20 N.A. 6.6 N.A. N.A. 26.6 N.A. 33.3 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 10 0 0 0 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 19 0 0 10 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 19 10 0 10 0 10 0 0 0 10 % F
% Gly: 0 0 0 37 10 46 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 10 10 19 10 19 10 19 10 % H
% Ile: 0 10 0 0 0 10 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 10 0 0 0 0 0 10 0 % K
% Leu: 10 10 0 0 10 0 0 0 10 0 0 0 0 46 10 % L
% Met: 0 0 0 0 46 0 37 0 0 10 0 0 0 10 0 % M
% Asn: 0 10 0 0 0 0 0 0 37 0 10 0 0 10 0 % N
% Pro: 19 37 37 10 0 10 19 0 0 0 10 0 10 0 10 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 46 10 28 19 0 10 10 46 10 10 0 19 10 0 0 % S
% Thr: 19 0 0 10 10 0 0 0 19 46 0 37 46 0 46 % T
% Val: 0 19 10 0 10 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 46 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _