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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ONECUT2 All Species: 16.06
Human Site: S259 Identified Species: 35.33
UniProt: O95948 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95948 NP_004843.2 504 54303 S259 P G H D K M L S P N F D A H H
Chimpanzee Pan troglodytes XP_523935 499 54831 S254 P G H D K M L S P N F D A H H
Rhesus Macaque Macaca mulatta XP_001087035 1137 121923 S892 P G H D K M L S P N F D A H H
Dog Lupus familis XP_541087 307 34190 T70 P N F D A H H T A M L T R G E
Cat Felis silvestris
Mouse Mus musculus Q6XBJ3 505 54536 S260 P G H D K M L S P N F D A H H
Rat Rattus norvegicus P70512 465 51049 H229 H P A M L G R H G E Q H L T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510495 398 44524 M162 F D A H H T A M L A R G D Q H
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002661005 441 48471 M205 G F E S H A A M L S R S E E H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NJB5 1081 117679 Q686 Q Y F L D K S Q E P S S V V A
Honey Bee Apis mellifera XP_624996 770 74637 S512 Y S Q S G L N S P H K S A S P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999824 483 51431 N242 L T A P M V L N G L S G H P H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.7 43.7 59.7 N.A. 98.6 61.3 N.A. 69.4 N.A. N.A. 62.2 N.A. 25 31.6 N.A. 42.8
Protein Similarity: 100 79.9 44 60.3 N.A. 98.8 70.6 N.A. 72.4 N.A. N.A. 70.8 N.A. 33.1 39 N.A. 52.7
P-Site Identity: 100 100 100 13.3 N.A. 100 0 N.A. 6.6 N.A. N.A. 6.6 N.A. 0 20 N.A. 13.3
P-Site Similarity: 100 100 100 20 N.A. 100 0 N.A. 6.6 N.A. N.A. 13.3 N.A. 0 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 28 0 10 10 19 0 10 10 0 0 46 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 46 10 0 0 0 0 0 0 37 10 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 10 10 0 0 10 10 10 % E
% Phe: 10 10 19 0 0 0 0 0 0 0 37 0 0 0 0 % F
% Gly: 10 37 0 0 10 10 0 0 19 0 0 19 0 10 0 % G
% His: 10 0 37 10 19 10 10 10 0 10 0 10 10 37 64 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 37 10 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 0 0 10 10 10 46 0 19 10 10 0 10 0 0 % L
% Met: 0 0 0 10 10 37 0 19 0 10 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 10 10 0 37 0 0 0 0 0 % N
% Pro: 46 10 0 10 0 0 0 0 46 10 0 0 0 10 19 % P
% Gln: 10 0 10 0 0 0 0 10 0 0 10 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 19 0 10 0 0 % R
% Ser: 0 10 0 19 0 0 10 46 0 10 19 28 0 10 0 % S
% Thr: 0 10 0 0 0 10 0 10 0 0 0 10 0 10 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _