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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGBL1
All Species:
35.76
Human Site:
S233
Identified Species:
78.67
UniProt:
O95965
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95965
NP_004782.1
494
53921
S233
E
S
K
R
R
C
T
S
P
D
G
K
I
C
S
Chimpanzee
Pan troglodytes
XP_001150034
494
53943
S233
E
S
K
R
R
C
T
S
P
D
G
K
I
C
S
Rhesus Macaque
Macaca mulatta
XP_001093345
494
53956
S233
E
S
K
R
R
C
T
S
P
D
G
K
I
C
S
Dog
Lupus familis
XP_542655
494
53634
S233
E
S
K
R
R
C
T
S
P
D
G
K
I
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDV0
494
53960
S233
E
S
K
R
R
C
T
S
P
D
G
K
V
C
S
Rat
Rattus norvegicus
Q5PQQ8
494
53886
S233
E
S
K
R
R
C
T
S
P
D
G
K
V
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513627
493
53321
S232
E
S
K
R
R
C
T
S
P
D
G
K
I
C
S
Chicken
Gallus gallus
XP_416966
490
53066
S229
E
I
K
K
R
C
T
S
P
D
G
K
I
C
S
Frog
Xenopus laevis
Q5M9B3
488
53111
S227
E
I
K
K
R
C
T
S
P
D
G
K
I
C
S
Zebra Danio
Brachydanio rerio
NP_001019243
428
46906
G196
G
H
G
K
C
Y
C
G
N
C
Y
C
S
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27874
809
90119
E433
E
G
I
R
V
G
D
E
V
Q
F
E
V
T
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.9
93.3
N.A.
90.8
91.3
N.A.
85.4
79.5
78.3
52.6
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
100
99.5
99.3
96.3
N.A.
95.1
95.3
N.A.
92.9
88.4
87.8
64.9
N.A.
N.A.
N.A.
31.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
86.6
86.6
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
6.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
10
82
10
0
0
10
0
10
0
82
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
82
0
0
0
0
0
% D
% Glu:
91
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
10
10
10
0
0
10
0
10
0
0
82
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
10
0
0
0
0
0
0
0
0
0
64
0
0
% I
% Lys:
0
0
82
28
0
0
0
0
0
0
0
82
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
73
82
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
64
0
0
0
0
0
82
0
0
0
0
10
0
82
% S
% Thr:
0
0
0
0
0
0
82
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
10
0
0
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _